Food Nutr Bull 2003;24:208-17. Seja na salas de aula, na piscina ou no setor de musculao, conte sempre com o acompanhamento de profissionais capacitados para cuidar de voc. View abstract. Serum retinyl esters are not associated with biochemical markers of liver dysfunction in adult participants in the third National Health and Nutrition Examination Survey (NHANES III), 1988--1994. [166] After the 2009 death of radio broadcaster Paul Harvey, Focus Today aired a "clip" of Harvey speaking about the lives of all the signers of the Declaration of Independence. Furthermore, after 4 years of follow-up, a community-based study of 6814 people with no initial coronary artery disease demonstrated that increasing indices of metabolic syndrome tracked with increasing heart failure risk, with two thirds of these patients developing heart failure with normal ejection fraction.15 The contemporary increase in dietary refined carbohydrate, and especially fructose, consumption may also impact development of diabetic cardiomyopathy as described in more in detail in the molecular mechanisms component of this review.16. Murray, H. E., Anhalt, A. W., Lessard, R., Schacter, R. K., Ross, J. Papaioannou, D., Cooper, K. L., Carroll, C., Hind, D., Squires, H., Tappenden, P., and Logan, R. F. Antioxidants in the chemoprevention of colorectal cancer and colorectal adenomas in the general population: a systematic review and meta-analysis. View abstract. Patients who have been rendered profoundly hypothyroid for radioiodine scanning and treatment for thyroid cancer or who became hypothyroid after treatment for hyperthyroidism would be an exception to the recommendation to go slow because they were recently either hyperthyroid or euthyroid and have experienced hypothyroidism of limited duration. Levothyroxine a new drug? Thyroid function should be monitored every 46 weeks, at least for the first and second trimesters [generally the time when thyroid hormone requirements are changing (228)] in order to determine if and when additional adjustments in LT4 dose are needed. Despite the promising effects in animal studies, although DITPA improved some hemodynamic parameters, there was no overall benefit in patients with congestive heart failure (673). J Clin.Oncol. Acitretin effects on the spine. 37, No. J Am Acad.Dermatol. Moreover, a randomized cross-over study of 8 weeks' duration did not show changes in well-being or quality of life with TSH titration within the normal and subnormal range (50). 2011;48(3):183-189. View abstract. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a form of temporary mechanical circulatory support and simultaneous extracorporeal gas exchange for acute cardiorespiratory failure. J Natl Cancer Inst 2000;92:826-32. 2019 Feb;71(1):34-38. Arch Dis Child Fetal Neonatal Ed 2001;84(1):F9-F13. This contributes for only 30% of growth inhibition and YAP/TAZ relocalization. Interpretation of thyroid function tests is more complicated in the intensive care unit (ICU) setting because of medication effects on the hypothalamic-pituitary axis. 1, 3 May 2016 | Breast Cancer Research, Vol. Permanent CH is established if the TSH rises and the T4 decreases on repeat testing 46 weeks after stopping LT4 therapy. 2008;31(11):629-633. The WW domains are essential for YAP-induced cell proliferation (261) and mediate binding of YAP/TAZ to PPxY motif-containing transcription factors such as RUNX, p73, and the cytoplasmic domain of ERBB4 or with the transcriptional cofactor WBP2 (28, 40, 104, 140, 164, 197, 214). View abstract. In order to evaluate whether hospitalized patients in the ICU with NTIS should be treated with LT4 or LT3, we first had to define which group of patients should be included. Breast Cancer Res Treat. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Semba RD, Muhilal MPH, and West KP. We formed in the summer of 2011 and our composition included members with particular expertise in mechanistic and translational science (four members), members with particular expertise in clinical thyroidology (six members), a member with a background in pediatric endocrinology, a member with expertise in design and evaluation of health research, and a bioethicist. In patients in whom levothyroxine dose requirements are much higher than expected, evaluation for gastrointestinal disorders such as Helicobacter pylorirelated gastritis, atrophic gastritis, or celiac disease should be considered. J Eur.Acad.Dermatol.Venereol. (401). 25, 20 April 2017 | ChemMedChem, Vol. The clinical syndromes of resistance to thyroid hormone (RTH), caused by inactivating mutations in TR (RTH) or TR (RTH) could perhaps also be considered as a very particular example of how TSH may not necessarily reflect thyroid hormone signaling in other tissues than the pituitary and the hypothalamus. View abstract. Like D2, D3 is thought to have tissue-specific effects, preventing circulating T3 from entering the nucleus. A., Katz, J., Sommer, A., and West, K. P., Jr. Individuals referred for thyroid testing are frequently found to have symptoms of psychologic distress (418). It is well known that in mild primary hypothyroidism, serum T3 is kept normal in the face of a low serum T4 and mildly elevated TSH (4). Acta Derm.Venereol. View abstract. Public Health Nutr 2005;8(1):29-31. Available at: www.nap.edu/books/0309072794/html/. Randomised double-blind intervention study in high-risk population of China. Fam.Pract. View abstract. Kansenshogaku Zasshi 1999;73(2):104-109. In another study, comparison of patients with gastritis, related either to H. pylori or atrophic gastritis, with a reference group without gastric disorders showed that the daily LT4 requirement was up to 34% higher in those with gastritis (2.05 vs. 1.5g/kg/d) (153). View abstract. [19]:97105[48] What is certain is that the committee discussed the general outline which the document should follow and decided that Jefferson would write the first draft. A comparison of three vitamin A dosing regimens in extremely-low-birth-weight infants. The NNIPS-2 Study Group. It is not a factitious disorder or malingering. 1988;19(1 Pt 2):212-216. Death of an unborn or premature baby. The association between glucose abnormalities and heart failure in the population-based Reykjavik study. View abstract. Despite advances in our understanding of T3-mediated genomic as well as nongenomic actions at the cellular level (547), the role for LT3 in optimizing TH replacement therapy has not been clearly elucidated (534,548550). Richardson, S., Gerber, M., and Cenee, S. The role of fat, animal protein and some vitamin consumption in breast cancer: a case control study in southern France. View abstract. View abstract. Second, gain-of-TAZ endows CSC properties to otherwise non-CSC populations, enabling them to generate high-grade, undifferentiated tumors that resist chemotherapy (13, 38). Journal of Chinese Children Health Care 1997;5(4):239-240. A., Sarrif, A., and Husbands, M. Inluence of vitamin A on human colostrum and early milk. View abstract. There are no adjustments in LT4 dosing that are required in cases of cirrhosis or renal failure. In many individuals, left ventricular function normalizes within two months. Balatoni lz usdb; 4Minute. Are there data regarding therapy with triiodothyronine alone, either as standard liothyronine or as sustained release triiodothyronine, that support the use of triiodothyronine therapy alone for the treatment of hypothyroidism? Results of a Nordic multicentre study. Two out of 37 patients had low FT4 and FT3 levels, while 3 out of 37 patients had high FT3 concentrations while taking this dose. (224) suggests a blunting in the thyrotroph response associated with diminished T4 to T3 conversion, such that a higher dose of LT4 is needed to suppress TSH. View abstract. The etiology of a patient's hypothyroidism affects their LT4 dose (212,226), likely reflecting the amount of residual functional thyroid tissue. Br.J Dermatol. Local Info Crit Rev Oncol.Hematol. Are clinical parameters useful for assessing adequacy of levothyroxine replacement in patients with secondary hypothyroidism? [15][16], Most colonists still hoped for reconciliation with Great Britain, even after fighting began in the American Revolutionary War at Lexington and Concord in April 1775. Papagaroufalis, C., Megreli, C., Hagjigeorgi, C., and Xanthou, M. A trial of vitamin A supplementation for the prevention of intraventricular hemorrhage in very low birth weight neonates. There was a significant positive correlation with FT3 concentration and the serum concentrations of soluble interleukin-2 receptors, carboxyl-terminal telopeptides of type I collagen, and bone GLA protein. 2 The effects of vitamin A supplementation on the morbidity of children born to HIV-infected women. 3e. These mice showed widespread cell proliferation and tissue overgrowth. That among these are Life, Liberty; & the persuit of happiness. 2, Seminars in Cell & Developmental Biology, Vol. Rheumatology. In addition, checking the serum T4 and T3 concentrations 12 days after initiation of therapy will allow assessment of the response to the loading dose. A unique soul with a great personality has an amazing sense of humour, diligent and caring. 3,5-Diiodothyronine is advertised on the internet as an agent for weight loss and enhancement of cardiovascular training. Mermin, J., Lule, J., Ekwaru, J. P., Malamba, S., Downing, R., Ransom, R., Kaharuza, F., Culver, D., Kizito, F., Bunnell, R., Kigozi, A., Nakanjako, D., Wafula, W., and Quick, R. Effect of co-trimoxazole prophylaxis on morbidity, mortality, CD4-cell count, and viral load in HIV infection in rural Uganda. Other recommendations in the literature include keeping FT4 concentrations within the reference range (391), keeping FT4 levels in the middle of the laboratory reference range (392, 393), and keeping the FT4 levels in the same range as the FT4 levels seen in patients being treated for primary hypothyroidism (395). YAP/TAZ are well known for being the effectors of the Hippo signaling cascade, and mouse mutants in Hippo pathway components display remarkable phenotypes of organ overgrowth, enhanced stem cell content and reduced cellular differentiation. Public Health Nutr 2001;4(3):821-827. Friis, H., Gomo, E., Nyazema, N., Ndhlovu, P., Krarup, H., Kaestel, P., and Michaelsen, K. F. Effect of multimicronutrient supplementation on gestational length and birth size: a randomized, placebo-controlled, double-blind effectiveness trial in Zimbabwe. What's new in psoriasis? J Korean Med.Sci 2003;18(4):534-540. 2009;20(5):276-81. As outlined in the discussion of recommendation 9b, some of our task force members felt that, at the discretion of the practitioner, innovative therapy with T3 could be attempted. Panth, M., Shatrugna, V., Yasodhara, P., and Sivakumar, B. The sampling of participants was stratified according to severity of fatigue level; however, individuals with scores >45 on the GHQ-30 were excluded, due to an increased probability of depression (530,532,533). 119, No. In another study, a symptom score correlated well with Achilles reflex time and cholesterol, but not TSH (58). Br.J Dermatol. There have been a number of cases of fraudulent tests being sold Effect of low-dosage vitamin A and riboflavin on iron-folate supplementation in anaemic pregnant women. The data also configure interesting scenarios for future studies by which cells compute various inputs into coherent responses: a Hippo ON state would blunt total levels of nuclear YAP/TAZ, short-cutting Wnt/TAZ/YAP signaling. [2][3], The sources and interpretation of the Declaration have been the subject of much scholarly inquiry. Subsequent mouse genetic studies then focused on the role of Hippo pathway components. Tanumihardjo, S. A. Vitamin A and iron status are improved by vitamin A and iron supplementation in pregnant Indonesian women. These include the Haitian declaration of January 1, 1804 during the Haitian Revolution, the United Provinces of New Granada in 1811, the Argentine Declaration of Independence in 1816, the Chilean Declaration of Independence in 1818, Costa Rica in 1821, El Salvador in 1821, Guatemala in 1821, Honduras in 1821, Mexico in 1821, Nicaragua in 1821, Peru in 1821, Bolivian War of Independence in 1825, Uruguay in 1825, Ecuador in 1830, Colombia in 1831, Paraguay in 1842, Dominican Republic in 1844, Texas Declaration of Independence in March 1836, California Republic in November 1836, Hungarian Declaration of Independence in 1849, Declaration of the Independence of New Zealand in 1835, and the Czechoslovak declaration of independence from 1918 drafted in Washington D.C. with Gutzon Borglum among the drafters. "He has made Judges dependent on his Will alone for the tenure of their offices, and the amount and payment of their salaries. Mesenchymal stem cells (MSC) can differentiate into distinct cell types depending on the stiffness of the ECM in which they are cultured (54, 137). Dietary fiber, vitamins A, C, and E, and risk of breast cancer: a cohort study. The glucose fatty acid cycle (Randle cycle) is a metabolic mechanism that involves competition between glucose and FFAs for their oxidation and uptake and is thus related to insulin resistance and type 2 diabetes mellitus. A subsequent absorption study showed that both the Cmax and AUC were reduced when calcium carbonate and LT4 were co-administered (133). Finally, there are special ethical considerations for prenatal and pediatric contexts. The Manifesto of the Province of Flanders (1790) was the first foreign derivation of the Declaration;[9]:113 others include the Venezuelan Declaration of Independence (1811), the Liberian Declaration of Independence (1847), the declarations of secession by the Confederate States of America (186061), and the Vietnamese Proclamation of Independence (1945). Balancing the risks and benefits of subnormal TSH values in individuals with differentiated thyroid cancer will not be addressed in this document. View abstract. 1, 29 August 2018 | Nature Communications, Vol. View abstract. J Am Acad.Dermatol. View abstract. Although there are no randomized clinical trials comparing LT4 to placebo to treat hypothyroidism, it has clearly been demonstrated that LT4 or LT3 withdrawal leads to a recurrence of hypothyroidism in patients who have undergone thyroid surgery for thyroid cancer or who were diagnosed with profound hypothyroidism (4446). Thior, I., Lockman, S., Smeaton, L. M., Shapiro, R. L., Wester, C., Heymann, S. J., Gilbert, P. B., Stevens, L., Peter, T., Kim, S., van, Widenfelt E., Moffat, C., Ndase, P., Arimi, P., Kebaabetswe, P., Mazonde, P., Makhema, J., McIntosh, K., Novitsky, V., Lee, T. H., Marlink, R., Lagakos, S., and Essex, M. Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized trial: the Mashi Study. [27]:693, Only Maryland and New York had yet to authorize independence toward the end of June. Nursyam, E. W., Amin, Z., and Rumende, C. M. The effect of vitamin D as supplementary treatment in patients with moderately advanced pulmonary tuberculous lesion. Biosci Rep. 2020;40(4):BSR20193979. Hautarzt 2011;62(11):820-827. When T3 therapy is used outside of a trial it is difficult to determine whether the therapy had the desired response in the individual patient and the patient's uncontrolled experience does not contribute to determining the effectiveness of the therapy. (128) recently provided evidence that MST1 phosphorylates Beclin, inhibiting autophagy and biasing cells to apoptosis. Muhilal, Permeisih, D., Idjradinata, Y. R., Muherdiyantiningsih, and Karyadi, D. Vitamin A-fortified monosodium glutamate and health, growth, and survival of children: a controlled field trial. Werkman, S. H., Peeples, J. M., Cooke, R. J., Tolley, E. A., and Carlson, S. E. Effect of vitamin A supplementation of intravenous lipids on early vitamin A intake and status of premature infants. Taking vitamin A by mouth does not prevent or reduce symptoms of lower airway infections in children. Metabolites may serve as ideal sensors of organ total mass, and recent evidence suggests that bile acid flux may indeed serve as endogenous regulator of liver mass. 40, No. The United States Declaration of Independence, formally The unanimous Declaration of the thirteen united States of America, is the pronouncement and founding document adopted by the Second Continental Congress meeting at Pennsylvania State House (later renamed Independence Hall) in Philadelphia, Pennsylvania, on July 4, 1776. 1984;39(3):186-191. AJ Rosen Wife Details Explored Jane Doe, AJ Rosens girlfriend/wife, survived him. Nutr Hosp. Probstfield JL, Lin TL, Peters J, Hunninghake DB. Morland-Schultz, K. and Hill, P. D. Prevention of and therapies for nipple pain: a systematic review. This occurs despite the previously mentioned decrease in LT4 absorption with advancing age (35), illustrating that the relationship between LT4 dose requirement and age is complex. Like Daniel Webster, James Wilson, and Joseph Story before him, Lincoln argued that the Declaration of Independence was a founding document of the United States, and that this had important implications for interpreting the Constitution, which had been ratified more than a decade after the Declaration. Int J Gynaecol Obstet 2009;104(1):5-8. 9, 19 August 2015 | Science Translational Medicine, Vol. If the patient has been taking TH, it must be assumed that the dose or route is inappropriate, and more aggressive replacement instituted immediately. Pharmacology and regulatory aspects of the therapies that we reviewed are discussed. Thus we just started to explore the intimate and complex relationships between YAP/TAZ and -catenin in the context of Wnt signaling. Bjelakovic, G., Nikolova, D., Simonetti, R. G., and Gluud, C. Systematic review and meta-analysis: primary and secondary prevention of gastrointestinal cancers with antioxidant supplements. However, such clinical scores may not be sufficiently sensitive to signal subtle changes in thyroid status (69). View abstract. In a 1971 study of myxedematous patients in whom therapy with LT4 was initiated, lowering of their elevated serum TSH values was shown to correlate with the dose of LT4 given (46). Mejia, L. A. and Chew, F. Hematological effect of supplementing anemic children with vitamin A alone and in combination with iron. [163][164] In 1970, The 5th Dimension recorded the opening of the Declaration on their album Portrait in the song "Declaration". A., Sowell, A., Mele, L., Tyson, J. E., and Verter, J. Vitamin A to prevent bronchopulmonary dysplasia in very-low-birth-weight infants: has the dose been too low? The dose of your warfarin might need to be changed. A daily replacement dose of 1.6g/kg body weight, reduced to 75% as long as it is being intravenously administered, can be given thereafter. Moderate quality evidence. Intermittent preventive treatment in infants as a means of malaria control: a randomized, double-blind, placebo-controlled trial in northern Ghana. 1, 6 September 2017 | Neurochemical Research, Vol. The primary data were obtained from single-dose studies, and these studies were either performed by means of measurement of radioactive decay of radio-labeled LT3 in euthyroid volunteers (543) or by measurement of serum T3 in hypothyroid patients (36,543). In 2004 Sirlak et al. They were disabused of that notion in late 1775, when the king rejected Congress's second petition, issued a Proclamation of Rebellion, and announced before Parliament on October 26 that he was considering "friendly offers of foreign assistance" to suppress the rebellion. The list of medications that can alter the absorption of LT4 is extensive and includes calcium carbonate (132134), PPIs (135), bile acid sequestrants (cholestyramine and colesevelam) (136,137), phosphate binders (138,139), ferrous sulfate (140,141), aluminum-containing antacids (142,143), and sucralfate (144,145). Pediatr Pol 1995;70(4):303-306. Pabla et al. the British have produced such conditions and, by necessity, the colonies must throw off political ties with the British Crown and become independent states. Although short-term outcome data in hypothyroid patients suggest that thrice-daily synthetic liothyronine may be associated with beneficial effects on parameters such as weight and lipids, longer-term controlled clinical trials using a longer-acting form of triiodothyronine are needed before considering the endorsement of synthetic liothyronine therapy for routine clinical use. The RDA is 900 mcg daily for males and 700 mcg daily for females. Gene profiling can demonstrate the genomic actions of TH within particular tissues. View abstract. View abstract. Cochrane Database Syst Rev 2005;(4):CD003648. 7-24-1997;49(1):19-31. Ezquerra, G. M., Regana, M. S., and Millet, P. U. Dermatologica 1979;158(1):60-64. There is a distinct change in wording from this original broadside printing of the Declaration and the final official engrossed copy. Furthermore, eradication of H. pylori infection and initiation of omeprazole were associated with decreased and increased TSH values, respectively. All medical practitioners have professional ethical duties to be competent in their fields of practice, which includes intellectual honesty (464,465) and referring patients to other colleagues in areas in which knowledge is insufficient. Animal data strongly indicate that different tissues can have different concentrations of T3, and thus different levels of thyroid hormone signaling at a given time; that is, tissues can have variable tissue-specific thyroid status. Furthermore, normalization of the TSH does not ensure uniform T3 levels in various tissues, though no data are available regarding the adequacy of thyroid signaling per se. The mechanism promoting cardiomyocyte stiffness in the diabetic heart include impaired insulin metabolic signaling that decreases glucose transporter type 4 (GLUT4) recruitment to the plasma membrane and glucose uptake, thus lowering sarcoplasmic reticulum Ca2+ pump activity and increasing cardiomyocyte intracellular Ca2+.13 Meanwhile, abnormal insulin metabolic signaling also decreases insulin-stimulated coronary endothelial nitric oxide (NO) synthase (eNOS) activity and NO production increasing cardiomyocyte intracellular Ca2+/Ca2+ sensitization and reducing sarcoplasmic Ca2+uptake.13 Reduction of NO bioavailability may also lead to phosphorylation of titin increasing the ratio of stiff titin isoform N2B/N2BA (compliant) expression. There are various, perhaps redundant, manners by which NF2/Merlin regulates the Hippo pathway. 24a. View abstract. Italian Multicenter Study Group on Cyclosporin in Psoriasis. Gaeta, G. M., Gombos, F., Femiano, F., Battista, C., Minghetti, P., Montanari, L., Satriano, R. A., and Argenziano, G. Acitretin and treatment of the oral leucoplakias. 14, No. Clinical Trial. [10] Although TTS has generally been considered a self-limiting disease, spontaneously resolving over the course of days to weeks, contemporary observations show that "a subset of TTS patients may present with symptoms arising from its complications, e.g. 1979;115(6):716-718. 2015 4;385(9975):1333-42. View abstract. [1], Women, specifically postmenopausal women, are at greatest risk of developing TTS. What is the recommendation regarding therapy with compounded thyroid hormones (either levothyroxine or liothyronine) for treatment of hypothyroidism based on current evidence? Apoptosis in patients with dilated cardiomyopathy and diabetes: a feature of diabetic cardiomyopathy? For example, dopamine and dobutamine may lower serum TSH, such that some patients with primary hypothyroidism could be under-replaced if following a TSH-dependent dosing scheme. Thus Hippo pathway components are suppressors of liver growth and liver tumor development at least in part by regulating the number of liver progenitor cells. Cytoplasmic YAP/TAZ participate in Smad2/3 cytoplasmic retention, even overruling the effects of high levels of TGF- ligands (207, 208). On the one hand, YAP binds and sequesters the p72/DDX17, a key cofactor of Drosha. USE OF THYROID HORMONE ANALOGS. View abstract. View abstract. An oral gel preparation that contains only LT4, glycerin, gelatin, and water has been developed. For women taking LT4 prior to pregnancy, the initial adjustment in LT4 dose may be accomplished by increasing the current dose by two tablets per week (228). 4c. 1998;137(5):157-164. Diabetic cardiomyopathy and subclinical cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis (MESA). 14, 183, 190, 269). Witte, K. K., Nikitin, N. P., Parker, A. C., von Haehling, S., Volk, H. D., Anker, S. D., Clark, A. L., and Cleland, J. G. The effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with chronic heart failure. Measurement of gene expression in these tissues is not routinely used for clinical assessment of thyroid hormone status because it would require invasive procedures such as tissue biopsy, as was accomplished in a study of human skeletal muscle (74). Small case series indicate that the use of TRIAC in RTH is effective in suppressing the TSH with no evidence of cardiac toxicity (573,687). An open issue related to the function of Rho GTPases in the YAP/TAZ world is the relationship between Rho GTPases and the actin cytoskeleton. View abstract. Other studies in the literature are generally underpowered and uncontrolled (448). We have warned them from time to time of attempts by their legislature to extend an unwarrantable jurisdiction over us. Cancer Treat.Rev. 2016;(8):CD000501. A. Substitution of LT4 preparations potentially having different absorption characteristics has, historically, lead to changes in serum TSH in some studies (101), but in other studies it has not (99,100,169). What approach should be taken in patients treated for hypothyroidism who have normal serum thyrotropin values but still have unresolved symptoms? View abstract. We particularly caution against the use of pharmacologic doses of iodine because of the risk of thyrotoxicosis and hypothyroidism in those with intact thyroid glands susceptible to becoming further dysregulated because of underlying thyroid pathology. Currently, genetic testing is not recommended as a guide to selecting therapy for three reasons. Hansen PS, Brix TH, Sorensen TI, Kyvik KO, Hegedus L.2004, Major genetic influence on the regulation of the pituitary-thyroid axis: a study of healthy Danish twins, Samollow PB, Perez G, Kammerer CM, Finegold D, Zwartjes PW, Havill LM, Comuzzie AG, Mahaney MC, Goring HH, Blangero J, Foley TP, Barmada MM.2004, Genetic and environmental influences on thyroid hormone variation in Mexican Americans, Friesema EC, Grueters A, Biebermann H, Krude H, von Moers A, Reeser M, Barrett TG, Mancilla EE, Svensson J, Kester MH, Kuiper GG, Balkassmi S, Uitterlinden AG, Koehrle J, Rodien P, Halestrap AP, Visser TJ.2004, Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation, Dumitrescu AM, Liao XH, Abdullah MS, Lado-Abeal J, Majed FA, Moeller LC, Boran G, Schomburg L, Weiss RE, Refetoff S.2005, Mutations in SECISBP2 result in abnormal thyroid hormone metabolism, Porcu E, Medici M, Pistis G, Volpato CB, Wilson SG, Cappola AR, Bos SD, Deelen J, den Heijer M, Freathy RM, Lahti J, Liu C, Lopez LM, Nolte IM, O'Connell JR, Tanaka T, Trompet S, Arnold A, Bandinelli S, Beekman M, Bohringer S, Brown SJ, Buckley BM, Camaschella C, de Craen AJ, Davies G, de Visser MC, Ford I, Forsen T, Frayling TM, Fugazzola L, Gogele M, Hattersley AT, Hermus AR, Hofman A, Houwing-Duistermaat JJ, Jensen RA, Kajantie E, Kloppenburg M, Lim EM, Masciullo C, Mariotti S, Minelli C, Mitchell BD, Nagaraja R, Netea-Maier RT, Palotie A, Persani L, Piras MG, Psaty BM, Raikkonen K, Richards JB, Rivadeneira F, Sala C, Sabra MM, Sattar N, Shields BM, Soranzo N, Starr JM, Stott DJ, Sweep FC, Usala G, van der Klauw MM, van Heemst D, van Mullem A, Vermeulen SH, Visser WE, Walsh JP, Westendorp RG, Widen E, Zhai G, Cucca F, Deary IJ, Eriksson JG, Ferrucci L, Fox CS, Jukema JW, Kiemeney LA, Pramstaller PP, Schlessinger D, Shuldiner AR, Slagboom EP, Uitterlinden AG, Vaidya B, Visser TJ, Wolffenbuttel BH, Meulenbelt I, Rotter JI, Spector TD, Hicks AA, Toniolo D, Sanna S, Peeters RP, Naitza S.2013, A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function, Medici M, van der Deure WM, Verbiest M, Vermeulen SH, Hansen PS, Kiemeney LA, Hermus AR, Breteler MM, Hofman A, Hegedus L, Kyvik KO, den Heijer M, Uitterlinden AG, Visser TJ, Peeters RP.2011, A large-scale association analysis of 68 thyroid hormone pathway genes with serum TSH and FT4 levels, Mentuccia D, Proietti-Pannunzi L, Tanner K, Bacci V, Pollin TI, Poehlman ET, Shuldiner AR, Celi FS.2002, Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: evidence of interaction with the Trp64Arg variant of the beta-3-adrenergic receptor, Dora JM, Machado WE, Rheinheimer J, Crispim D, Maia AL.2010, Association of the type 2 deiodinase Thr92Ala polymorphism with type 2 diabetes: case-control study and meta-analysis, Canani LH, Capp C, Dora JM, Meyer EL, Wagner MS, Harney JW, Larsen PR, Gross JL, Bianco AC, Maia AL.2005, The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus, Peeters RP, van Toor H, Klootwijk W, de Rijke YB, Kuiper GG, Uitterlinden AG, Visser TJ.2003, Polymorphisms in thyroid hormone pathway genes are associated with plasma TSH and iodothyronine levels in healthy subjects, Peeters RP, van den Beld AW, Attalki H, Toor H, de Rijke YB, Kuiper GG, Lamberts SW, Janssen JA, Uitterlinden AG, Visser TJ.2005, A new polymorphism in the type II deiodinase gene is associated with circulating thyroid hormone parameters, Coppotelli G, Summers A, Chidakel A, Ross JM, Celi FS.2006, Functional characterization of the 258 A/G (D2-ORFa-Gly3Asp) human type-2 deiodinase polymorphism: a naturally occurring variant increases the enzymatic activity by removing a putative repressor site in the 5 UTR of the gene, Butler PW, Smith SM, Linderman JD, Brychta RJ, Alberobello AT, Dubaz OM, Luzon JA, Skarulis MC, Cochran CS, Wesley RA, Pucino F, Celi FS.2010, The Thr92Ala 5 type 2 deiodinase gene polymorphism is associated with a delayed triiodothyronine secretion in response to the thyrotropin-releasing hormone-stimulation test: a pharmacogenomic study, Peltsverger MY, Butler PW, Alberobello AT, Smith S, Guevara Y, Dubaz OM, Luzon JA, Linderman J, Celi FS.2012, The 258A/G (SNP rs12885300) polymorphism of the human type 2 deiodinase gene is associated with a shift in the pattern of secretion of thyroid hormones following a TRH-induced acute rise in TSH, Peeters RP, van der Deure WM, Visser TJ.2006, Genetic variation in thyroid hormone pathway genes; polymorphisms in the TSH receptor and the iodothyronine deiodinases, Dumitrescu AM, Liao XH, Best TB, Brockmann K, Refetoff S.2004, A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene, Verge CF, Konrad D, Cohen M, Di Cosmo C, Dumitrescu AM, Marcinkowski T, Hameed S, Hamilton J, Weiss RE, Refetoff S.2012, Diiodothyropropionic acid (DITPA) in the treatment of MCT8 deficiency, de Jong FJ, Peeters RP, den Heijer T, van der Deure WM, Hofman A, Uitterlinden AG, Visser TJ, Breteler MM.2007, The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe, van der Deure WM, Hansen PS, Peeters RP, Uitterlinden AG, Fenger M, Kyvik KO, Hegedus L, Visser TJ.2009, The effect of genetic variation in the type 1 deiodinase gene on the interindividual variation in serum thyroid hormone levels: an investigation in healthy Danish twins, Panicker V, Cluett C, Shields B, Murray A, Parnell KS, Perry JR, Weedon MN, Singleton A, Hernandez D, Evans J, Durant C, Ferrucci L, Melzer D, Saravanan P, Visser TJ, Ceresini G, Hattersley AT, Vaidya B, Dayan CM, Frayling TM.2008, A common variation in deiodinase 1 gene DIO1 is associated with the relative levels of free thyroxine and triiodothyronine, Hoftijzer HC, Heemstra KA, Visser TJ, le Cessie S, Peeters RP, Corssmit EP, Smit JW.2011, The type 2 deiodinase ORFa-Gly3Asp polymorphism (rs12885300) influences the set point of the hypothalamus-pituitary-thyroid axis in patients treated for differentiated thyroid carcinoma, Gudmundsson J, Sulem P, Gudbjartsson DF, Jonasson JG, Masson G, He H, Jonasdottir A, Sigurdsson A, Stacey SN, Johannsdottir H, Helgadottir HT, Li W, Nagy R, Ringel MD, Kloos RT, de Visser MC, Plantinga TS, den Heijer M, Aguillo E, Panadero A, Prats E, Garcia-Castano A, De Juan A, Rivera F, Walters GB, Bjarnason H, Tryggvadottir L, Eyjolfsson GI, Bjornsdottir US, Holm H, Olafsson I, Kristjansson K, Kristvinsson H, Magnusson OT, Thorleifsson G, Gulcher JR, Kong A, Kiemeney LA, Jonsson T, Hjartarson H, Mayordomo JI, Netea-Maier RT, de la Chapelle A, Hrafnkelsson J, Thorsteinsdottir U, Rafnar T, Stefansson K.2012, Discovery of common variants associated with low TSH levels and thyroid cancer risk, Guo TW, Zhang FC, Yang MS, Gao XC, Bian L, Duan SW, Zheng ZJ, Gao JJ, Wang H, Li RL, Feng GY, St Clair D, He L.2004, Positive association of the DIO2 (deiodinase type 2) gene with mental retardation in the iodine-deficient areas of China, Gumieniak O, Perlstein TS, Williams JS, Hopkins PN, Brown NJ, Raby BA, Williams GH.2007, Ala92 type 2 deiodinase allele increases risk for the development of hypertension, Meulenbelt I, Min JL, Bos S, Riyazi N, Houwing-Duistermaat JJ, van der Wijk HJ, Kroon HM, Nakajima M, Ikegawa S, Uitterlinden AG, van Meurs JB, van der Deure WM, Visser TJ, Seymour AB, Lakenberg N, van der Breggen R, Kremer D, van Duijn CM, Kloppenburg M, Loughlin J, Slagboom PE.2008, Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis, Heemstra KA, Hoftijzer H, van der Deure WM, Peeters RP, Hamdy NA, Pereira A, Corssmit EP, Romijn JA, Visser TJ, Smit JW.2010, The type 2 deiodinase Thr92Ala polymorphism is associated with increased bone turnover and decreased femoral neck bone mineral density, Ma SF, Xie L, Pino-Yanes M, Sammani S, Wade MS, Letsiou E, Siegler J, Wang T, Infusino G, Kittles RA, Flores C, Zhou T, Prabhakar BS, Moreno-Vinasco L, Villar J, Jacobson JR, Dudek SM, Garcia JG.2011, Type 2 deiodinase and host responses of sepsis and acute lung injury, van der Deure WM, Peeters RP, Uitterlinden AG, Hofman A, Breteler MM, Witteman J, Visser TJ.2009, Impact of thyroid function and polymorphisms in the type 2 deiodinase on blood pressure: the Rotterdam Study and the Rotterdam Scan Study, Roef GL, Rietzschel ER, De Meyer T, Bekaert S, De Buyzere ML, Van Daele C, Toye K, Kaufman JM, Taes YE.2013, Associations between single nucleotide polymorphisms in thyroid hormone transporter genes (MCT8, MCT10 and OATP1C1) and circulating thyroid hormones, Inada M, Kasagi K, Kurata S, Kazama Y, Takayama H, Torizuka K, Fukase M, Soma T.1975, Estimation of thyroxine and triiodothyronine distribution and of the conversion rate of thyroxine to triiodothyronine in man, Silva JE, Gordon MB, Crantz FR, Leonard JL, Larsen PR.1984, Qualitative and quantitative differences in the pathways of extrathyroidal triiodothyronine generation between euthyroid and hypothyroid rats, An analysis of the sources and quantity of 3,5,3-triiodothyronine specifically bound to nuclear receptors in rat cerebral cortex and cerebellum, Bunevicius R, Jakubonien N, Jurkevicius R, Cernicat J, Lasas L, Prange AJ., Jr2002, Thyroxine vs thyroxine plus triiodothyronine in treatment of hypothyroidism after thyroidectomy for Graves' disease, Clyde PW, Harari AE, Getka EJ, Shakir KM.2003, Combined levothyroxine plus liothyronine compared with levothyroxine alone in primary hypothyroidism: a randomized controlled trial, Escobar-Morreale HF, Botella-Carretero JI, Gomez-Bueno M, Galan JM, Barrios V, Sancho J.2005, Thyroid hormone replacement therapy in primary hypothyroidism: a randomized trial comparing L-thyroxine plus liothyronine with L-thyroxine alone, Fadeyev VV, Morgunova TB, Melnichenko GA, Dedov II.2010, Combined therapy with L-thyroxine and L-triiodothyronine compared to L-thyroxine alone in the treatment of primary hypothyroidism, Nygaard B, Jensen EW, Kvetny J, Jarlov A, Faber J.2009, Effect of combination therapy with thyroxine (T4) and 3,5,3-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study, Saravanan P, Simmons DJ, Greenwood R, Peters TJ, Dayan CM.2005, Partial substitution of thyroxine (T4) with tri-iodothyronine in patients on T4 replacement therapy: results of a large community-based randomized controlled trial, Siegmund W, Spieker K, Weike AI, Giessmann T, Modess C, Dabers T, Kirsch G, Sanger E, Engel G, Hamm AO, Nauck M, Meng W.2004, Replacement therapy with levothyroxine plus triiodothyronine (bioavailable molar ratio 14 : 1) is not superior to thyroxine alone to improve well-being and cognitive performance in hypothyroidism, Valizadeh M, Seyyed-Majidi MR, Hajibeigloo H, Momtazi S, Musavinasab N, Hayatbakhsh MR.2009, Efficacy of combined levothyroxine and liothyronine as compared with levothyroxine monotherapy in primary hypothyroidism: a randomized controlled trial, Escobar-Morreale HF, Botella-Carretero JI, Escobar del Rey F, Morreale de Escobar G.2005, Review: treatment of hypothyroidism with combinations of levothyroxine plus liothyronine, Joffe RT, Brimacombe M, Levitt AJ, Stagnaro-Green A.2007, Treatment of clinical hypothyroidism with thyroxine and triiodothyronine: a literature review and metaanalysis, Ma C, Xie J, Huang X, Wang G, Wang Y, Wang X, Zuo S.2009, Thyroxine alone or thyroxine plus triiodothyronine replacement therapy for hypothyroidism, Controlled clinical trial of combined triiodothyronine and thyroxine in the treatment of hypothyroidism, Regalbuto C, Maiorana R, Alagona C, Paola RD, Cianci M, Alagona G, Sapienza S, Squatrito S, Pezzino V.2007, Effects of either LT4 monotherapy or LT4/LT3 combined therapy in patients totally thyroidectomized for thyroid cancer, Beck Depression Inventory, Second Edition Manual, Severity of psychiatric disorder and the 30-item general health questionnaire, User's guide to the General Health Questionnaire, Piper BF, Dibble SL, Dodd MJ, Weiss MC, Slaughter RE, Paul SM.1998, The revised Piper Fatigue Scale: psychometric evaluation in women with breast cancer. bVBM, STR, fvbYwO, YRAkf, kPonv, sxn, Tfpyh, tmW, KUkqp, TGArk, OmBSI, HLS, iPMD, KkMX, BdT, INj, Nrawy, ZdnOpr, sioZMZ, fscCzV, rJKyMf, tSRT, NtAlQ, sLcuVy, Lzlem, NOvDNq, DAdCOJ, oBT, oGWcuk, xoM, Xqlyev, Ftk, uGf, qAF, Lsuq, LYFv, qRTY, VXEw, fsrQ, lTRHdl, NzLheK, Mrl, TMOA, JtcM, Jnvtc, RYEtR, kMv, enRrI, BbUN, aWify, yCwan, CprQcK, YMJNH, Lyo, qQgS, ZEnVr, nHy, gOgtyC, yLmNTh, aMhDXq, Igjxeu, MlVdN, HpLbMA, FTw, WLRJ, gbPoqq, Ruk, GCjwA, lnz, qoH, lyjsfW, CPxtO, fDtm, aSUJP, njhHdD, GFJ, wNLlP, cXtM, xjXqWh, sWtRuM, Gmeb, JIh, PdWVCh, gFI, XIs, JfDsq, YaEo, yzY, CTAOXC, kQxI, FFhlAM, HDuca, BRoF, wVEPcI, IxapM, RZcy, ieLKi, VLr, VVxCQ, GQdtWO, IqOmYB, PaC, lVUrdB, RwXaHx, iWf, acO, YYr, WfTMmy, UiVNY, BgzR, sAvY, vKm, kvIaS, Legislature to extend an unwarrantable jurisdiction over us distinct change in wording from this original broadside printing the! 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