Selenium sulfide treats the excess shedding and irritation by eliminating excess scalp fungus and controlling the rate of shedding of dead skin cells. [25][26][27][28][29] However, application of selenium disulfide to damaged skin can result in systemic absorption and has been associated with cases of toxicity. [112], Trace elements involved in GSH-Px and superoxide dismutase enzymes activities, i.e. Do not leave on hair, scalp or skin for periods longer than directed and ensure all selenium sulfide is rinsed off well. [111] Marine organisms retained and sometimes expanded their selenoproteomes, whereas the selenoproteomes of some terrestrial organisms were reduced or completely lost. PHARMACOKINETICS: The mechanism of action of topically applied selenium sulfide is not yet known. Tetraselenium tetranitride, Se4N4, is an explosive orange compound analogous to tetrasulfur tetranitride (S4N4). National Research Council, Subcommittee on Sheep Nutrition (1985). [20], Selenium trioxide may be synthesized by dehydrating selenic acid, H2SeO4, which is itself produced by the oxidation of selenium dioxide with hydrogen peroxide:[22], Hot, concentrated selenic acid can react with gold to form gold(III) selenate.[23]. You need your mouth filled, something long and hard and fleshy sliding between your lips, over your tongue, and down your throat. A vdjegyzett ksztmnyek azonban nem egyetlen tiszta vegyletet tartalmaznak, hanem olyan keverket, melyben az Se:S arny sszessgben 1:2. [4], Selenium disulfide is sold as an antifungal agent in shampoos for the treatment of dandruff and seborrheic dermatitis associated in the scalp with fungi of genus Malassezia. [2] Systemic symptoms may include tremors, weakness, lethargy, lower abdominal pain, and occasional vomiting. Some of the selenium oxyhalides, such as selenium oxyfluoride (SeOF2) and selenium oxychloride (SeOCl2) have been used as specialty solvents. Its molecular structure consists of a ring of two selenium and six sulfur atoms, analogous to the S 8 allotrope of sulfur WebSulfeto de selnio ( portugus brasileiro) ou sulfeto de selnio ( portugus europeu) (mais precisamente dissulfeto de selnio ou sulfeto de selnio (IV)) o composto de frmula qumica SeS 2 . It has also been suggested that season could have an impact on the harmful effects of selenium on fish. In Belews Lake North Carolina, 19 species of fish were eliminated from the lake due to 150200g Se/L wastewater discharged from 1974 to 1986 from a Duke Energy coal-fired power plant. [24] Selenium reacts with fluorine to form selenium hexafluoride: In comparison with its sulfur counterpart (sulfur hexafluoride), selenium hexafluoride (SeF6) is more reactive and is a toxic pulmonary irritant. It seldom occurs in its elemental state or as pure ore compounds in the Earth's crust. [37] The developmental code name of selenium sulfide for these uses is AZR-MD-001 and it is being developed by Azura Ophthalmics. (Only the deiodinase iodotyrosine deiodinase, which works on the last breakdown products of thyroid hormone, does not use selenium. [21], Selenium disulfide should not be applied to damaged skin as there is a risk of systemic absorption and associated toxicity. [6] Selenium disulfide acts as a keratolytic and antifungal agent. [38][39][40] These lasted in commercial applications until the 1970s, following which they were replaced with less expensive and even more efficient silicon rectifiers. To the knowledge of researchers, there are no reports of mercury levels exceeding that of selenium levels in ocean fish. Though once widely used, selenium rectifiers have mostly been replaced (or are being replaced) by silicon-based devices. Apply to affected areas and lather with a small amount of water. It is a nonmetal (more rarely considered a metalloid) with properties that are intermediate between the elements above and below in the periodic table, sulfur and tellurium, and also has similarities to arsenic. WebSelenium disulfide is a bright orange colored powder. Anwar Hossain, Ken Touhata, Takeshi Yabu, and Yumiko Yamashita. This process leaches natural soluble selenium compounds (such as selenates) into the water, which may then be concentrated in wetlands as the water evaporates. In addition to controlling the symptoms Much below that level, young salmon die from deficiency;[135] much above, they die from toxic excess. Zinc selenide was the first material for blue LEDs, but gallium nitride dominates that market. The lithiumselenium (LiSe) battery is one of the most promising systems for energy storage in the family of lithium batteries. Selenium is a component of the unusual amino acids selenocysteine and selenomethionine. Selenium sulfide. During the 1980s, selenocysteine was shown to be encoded by the codon UGA. Its use as a photoconductor in plain-paper copiers once was a leading application, but in the 1980s, the photoconductor application declined (although it was still a large end-use) as more and more copiers switched to organic photoconductors. [15][16] The study found a 73% reduction in dandruff score with ketoconazole, a 67% reduction with selenium disulfide, and a 45% reduction with placebo. Five scenes of sweaty bull-bears, dad bods, and tatted Lets face it, sequels usually suck. The demand for selenium by the electronics industry is declining. INDICATIONS & USAGE: [142] Also, selenium interacts with other minerals, such as zinc and copper. Selenium from Common adverse reactions include . [7][21] The discoloration resolved shortly following discontinuation of selenium disulfide shampoo and its removal could be facilitated by lightly swabbing with isopropyl alcohol. There is no FDA guidance on the use of Selenium sulfide in patients with renal impairment. [134], The Occupational Safety and Health Administration (OSHA) has set the legal limit (permissible exposure limit) for selenium in the workplace at 0.2mg/m3 over an 8-hour workday. [3] Symptoms frequently return if treatment is stopped. [30], Many selenium sulfides are known, as indicated by 77Se-NMR spectroscopy. You can help Wikipedia by expanding it. What are the side effects of selenium sulfide? May be irritating to mucous membranes of the eyes and contact with this area should be avoided. Cybersocket Live Returns with Award Winner & Falcon/NakedSword Exclusive Beau Butler on 3/01/2022, Toon Tuesday: 5 Hot Cartoons from ChildhoodBut Now All Grown Up & Gay, 12 Gay Movies & TV Shows To Stream During Black History Month 2022, Zac Snow Wagged His Tail At Cybersockets Hot LA Underwear Party VPL, Bareback That Hole: Gaston Ccito Gives Up His Hairy Ass to Ethan Chase. WebIn OTC drug products, Selenium Sulfide also helps to control dandruff, seborrheic dermatitis and psoriasis. [7][8][9], The systemic absorption and toxicity of orally administered selenium sulfide has been studied in animals. Both organic and inorganic forms of selenium are largely converted to monosaccharide conjugates (selenosugars) in the body prior to elimination in the urine. the preparation of Se7). Selenium is found in metal sulfide ores, where it partially replaces the sulfur. )[123], Selenium may be measured in blood, plasma, serum, or urine to monitor excessive environmental or occupational exposure, to confirm a diagnosis of poisoning in hospitalized victims, or investigate a suspected case of fatal overdose. 1. There is limited information regarding Postmarketing Experience of Selenium sulfide in the drug label. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. Repeat this procedure once a day for seven days. High doses of Se supplements in pregnant animals might disturb the Zn:Cu ratio and lead to Zn reduction; in such treatment cases, Zn levels should be monitored. [78] Ionized selenium (Se+24) is one of the active mediums used in X-ray lasers. Selenium transmits an electric current proportional to the amount of light falling on its surface. See application instructions on rear panel of this bottle. [10][11] The packing is most dense in the form. |?Pill Size (mm) [43][44] In the 1970s, it was shown to be present in two independent sets of enzymes. [61] Its photovoltaic and photoconductive properties are still useful in photocopying,[73][74][75][76] photocells, light meters and solar cells. Applications in electronics, once important, have been mostly replaced with silicon semiconductor devices. [25] Selenium disulfide, also known as selenium sulfide, is a chemical compound and medication used to treat seborrheic dermatitis, dandruff, and pityriasis versicolor. [59][60], About 2,000tonnes of selenium were produced in 2011 worldwide, mostly in Germany (650t), Japan (630t), Belgium (200t), and Russia (140t), and the total reserves were estimated at 93,000tonnes. [18][19] In the United States, a 1% strength is available over-the-counter, and a 2.5% strength is also available with a prescription. [2], Selenium disulfide acts as an antifungal and keratolytic agent to treat seborrheic dermatitis and dandruff. In soils, selenium most often occurs in soluble forms such as selenate (analogous to sulfate), which are leached into rivers very easily by runoff. These materials are semiconductors. [143], In the regions (e.g. [6] Selenium disulfide acts as a keratolytic and antifungal agent. INDICATIONS: This product is a liquid antiseborrheic, antifungal preparation useful for the treatment of seborrheic dermatitis of the scalp, dandruff and tinea versicolor. Selenous acid can also be made directly by oxidizing elemental selenium with nitric acid:[20], Unlike sulfur, which forms a stable trioxide, selenium trioxide is thermodynamically unstable and decomposes to the dioxide above 185C:[7][20], Selenium trioxide is produced in the laboratory by the reaction of anhydrous potassium selenate (K2SeO4) and sulfur trioxide (SO3).[21]. Selenium disulfide, also known as selenium sulfide, is a chemical compound and medication used to treat seborrheic dermatitis, dandruff, and pityriasis versicolor. [64], Selenium is used with bismuth in brasses to replace more toxic lead. For the treatment of tinea versicolor, seborrheic dermatitis of the scalp, and dandruff. In high concentrations, selenium acts as an environmental contaminant. Their use continued into the 1990s. Other problems include degeneration of liver tissue, swelling around the heart, damaged egg follicles in ovaries, cataracts, and accumulation of fluid in the body cavity and head. There is no FDA guidance on the use of Selenium sulfide with respect to specific gender populations. Hazards What is this information? Iodides of selenium are not well known. Selenium sulfide topical (for the skin) is used to treat dandruff, seborrhea, and tinea Fish affected by selenium may experience swelling of the gill lamellae, which impedes oxygen diffusion across the gills and blood flow within the gills. Allow to remain on skin for 10 minutes. [19] In Canada, the 2.5% strength is available over-the-counter. [86], Selenium pollution might impact some aquatic systems and may be caused by anthropogenic factors such as farming runoff and industrial processes. Selenium dioxide is formed by the reaction of elemental selenium with oxygen:[7], It is a polymeric solid that forms monomeric SeO2 molecules in the gas phase. There is limited information regarding Off-Label Guideline-Supported Use of Selenium sulfide in adult patients. [89], Selenium poisoning of water systems may result whenever new agricultural run-off courses through dry lands. Deiodinases are able to extract electrons from iodides, and iodides from iodothyronines. Selenium sulfide is available as a 1% and 2.5% lotion and shampoo. [62], During the electrowinning of manganese, the addition of selenium dioxide decreases the power necessary to operate the electrolysis cells. Selenium sulfide, an anti-infective agent, relieves itching and flaking of the scalp and removes the dry, scaly particles that are commonly referred to as dandruff or seborrhea. The pyrite from the Falun Mine created a red precipitate in the lead chambers which was presumed to be an arsenic compound, so the pyrite's use to make acid was discontinued. [128] In China, people who ingested corn grown in extremely selenium-rich stony coal (carbonaceous shale) have suffered from selenium toxicity. [87] Fish are a major source of protein for humans, people who eat more fish are generally healthier than those who eat less, indicating selenium pollution does not appear to be a problem, although it might be useful to be aware that selenium has a potential effect on humans. |mainlabel=- Vegan Foods With SeleniumEnriched Foods. Certain products, such as pasta, whole wheat bread, and whole-grain cereal provide a good amount of selenium content as well as other important vitamins and minerals.Brown Rice. Sunflower Seeds. Baked Beans. Mushrooms. Oatmeal. Spinach. Lentils. Cashews. Bananas. More items They are, thus, involved in thyroid-hormone regulation, participating in the protection of thyrocytes from damage by H2O2 produced for thyroid-hormone biosynthesis. [8] It resists oxidation by air and is not attacked by nonoxidizing acids. There is no FDA guidance on the use of Selenium sulfide with respect to geriatric patients. Selenium is a component of the amino acids selenocysteine and selenomethionine. Selenium came to medical notice later because of its toxicity to industrial workers. Selenium sulfide Administration Type: Antiseborrheic Dosage Forms: Routes of Administration: Topical Common Trade Names: Adult Dosing Pityriasis versicolor: apply topically once daily, WebSELENIUM SULFIDE (se LEE nee um suhl fahyd) skin lotion is used to treat dandruff-like conditions, seborrhea, and psoriasis. [70], Amorphous selenium (-Se) thin films have found application as photoconductors in flat panel x-ray detectors. The National Institute for Occupational Safety and Health (NIOSH) has set a Recommended exposure limit (REL) of 0.2mg/m3 over an 8-hour workday. Also naturally occurring is the long-lived primordial radionuclide 82Se, with a half-life of 9.21019 years. [61][63], The largest commercial use of Se, accounting for about 50% of consumption, is for the production of glass. WHEN USED ON BODY SURFACES FOR THE TREATMENT OF TINEA VERSICOLOR, SELENIUM SULFIDE IS CLASSIFIED AS PREGNANCY CATEGORY "C". |?Pill Imprint On 19 April 2009, 21 polo ponies died shortly before a match in the United States Polo Open. [124], Although selenium is an essential trace element, it is toxic if taken in excess. Scientific Facts: Selenium is a naturally occurring mineral element found in rocks and soil. [31], Selenium sulfide was introduced for medical use in the United States in 1951.[5][19]. Native (i.e., elemental) selenium is a rare mineral, which does not usually form good crystals, but, when it does, they are steep rhombohedra or tiny acicular (hair-like) crystals. For External Use Only. [37][38][19] As of March 2021, it is in phase 2/3 clinical trials for meibomianitis and phase 2 trials for dry eyes. In June 2015, the US Food and Drug Administration (FDA) published its final rule establishing the requirement of minimum and maximum levels of selenium in infant formula. By using our services, you agree to our use of cookies. However, as used in proprietary formulations, it is not a pure chemical compound but a mixture of eight-membered-ring compounds where the overall Se:S ratio is 1:2. |mainlabel=- [5] It consists of a mixture of inorganic covalent compounds having an approximate empirical formulas of SeS2. China is the dominant consumer of selenium at 1,5002,000tonnes/year. 4. |?Pill Scoring [2] These symptoms usually resolve within 10days following exposure. Selenium pollution of waterways also occurs when selenium is leached from coal flue ash, mining and metal smelting, crude oil processing, and landfill. In humans, selenium is a trace element nutrient that functions as cofactor Common production from the residue then begins by oxidation with sodium carbonate to produce selenium dioxide, which is mixed with water and acidified to form selenous acid (oxidation step). One family of selenium-bearing molecules (the glutathione peroxidases) destroys peroxide and repairs damaged peroxidized cell membranes, using glutathione. [15] It was a three-arm trial of 246 people with moderate to severe dandruff and compared treatment with 2% ketoconazole shampoo (n=97), 2.5% selenium disulfide shampoo (n=100), and placebo (shampoo base with no antiseborrheic agent) (n=49) for 29days. For every tonne of manganese, an average 2kg selenium oxide is used. Author: Vanessa Ngan, Staff Writer, 2005. [125], Selenium (in close interrelation with iodine) plays a role in thyroid health. We all appreciate getting nice and sweaty at the gym, but what comes out must be put back in. Selenium sulfide is insoluble in water. [17], Selenium disulfide is available in the form of a prescription drug as a 2.5% medical shampoo. For other applications, a red color may be desired, produced by mixtures of CdSe and CdS. [2][3] It is applied to the affected area as a lotion or shampoo. The isomer n-butane can connect in two ways, giving rise to two "-butyl" groups: . In humans, selenium is a trace element nutrient that functions as cofactor for reduction of antioxidant enzymes, such as glutathione peroxidases[98] and certain forms of thioredoxin reductase found in animals and some plants (this enzyme occurs in all living organisms, but not all forms of it in plants require selenium). [1]; Associate Editor(s)-in-Chief: Adeel Jamil, M.D. There is no FDA guidance on the use of Selenium sulfide with respect to pediatric patients. [65] Like lead and sulfur, selenium improves the machinability of steel at concentrations around 0.15%. [114] About 200 million years ago, new selenoproteins were developed as mammalian GSH-Px enzymes. arrow-right-small-blue There is limited information regarding Monitoring of Selenium sulfide in the drug label. WebThe safety of topical selenium sulfide lotion in man has been demonstrated previously. Selenium sulfide has been used as an insecticide, fungicide, and herbicide. [7][26][27] It can be synthesized by the reaction of selenium tetrachloride (SeCl4) with [((CH3)3Si)2N]2Se. [121], The selenium content in the human body is believed to be in the 1320mg range. Selenium enzymes are involved in the small reducing molecules glutathione and thioredoxin. Selenium was also recognized as an important veterinary toxin, which is seen in animals that have eaten high-selenium plants. Urea hydrates and is useful for conditions such as dry scalp. [122], Certain species of plants are considered indicators of high selenium content of the soil because they require high levels of selenium to thrive. [149] However, in a case of combined iodine and selenium deficiency, selenium deficiency was shown to play a thyroid-protecting role. It prevents fungus from growing on your skin. In the film Evolution selenium was mentioned as an active ingredient of Head & Shoulders. With highly electropositive metals, such as aluminium, these selenides are prone to hydrolysis:[7]. Alcohol-Selenium sulfide interaction has not been established. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. Selenium sulfide 1% and 2.5% strengths are used on the scalp to help control the symptoms of dandruff and seborrheic dermatitis. [131] Hydrogen selenide is an extremely toxic, corrosive gas. [5] It is on the World Health Organization's List of Essential Medicines. Product may damage jewelry; remove jewelry before use. )[100], Selenium may inhibit Hashimoto's disease, in which the body's own thyroid cells are attacked as foreign. Selenium disulfide, also known as selenium sulfide, is a chemical compound and medication used to treat seborrheic dermatitis, dandruff, and pityriasis versicolor. Its been heated and argumentative, with fucking continue reading, Celebs like to tease us with a thirst trap every now or thensome dont even make it to grid, cause its just a tease. For the software testing framework, see, Chemical element, symbol Se and atomic number 34, A Se(0) atom has been identified using DFT in [ReOSe(2-pySe). If allergic reactions occur, discontinue use. [20][19], Side effects of selenium disulfide shampoo for dandruff appear to be infrequent. The first commercial products using selenium were developed by Werner Siemens in the mid-1870s. The regulation of lead in drinking water applications such as in the US with the Safe Drinking Water Act of 1974, made a reduction of lead in brass necessary. Extreme cases of selenosis can exhibit cirrhosis of the liver, pulmonary edema, or death. [145] Ruminants grazing certain forages, e.g., some white clover varieties containing cyanogenic glycosides, may have higher selenium requirements,[145] presumably because cyanide is released from the aglycone by glucosidase activity in the rumen[146] and glutathione peroxidases is deactivated by the cyanide acting on the glutathione moiety. DermNet does not provide an online consultation service. Topics AZ Animal reproduction studies have not been conducted with Selenium Sulfide Topical Suspension USP, 2.5% (Lotion). Hence, Berzelius's first letter to Alexander Marcet stated that this was a tellurium compound. [7][13], Owing to its use as a photoconductor in flat-panel x-ray detectors (see below), the optical properties of amorphous selenium (-Se) thin films have been the subject of intense research.[14][15][16]. Maybe something a bit too continue reading, Nothing like a healthy doctor visit, getting all checked out, make sure everythings in working order, inside and out. [24][7] Topical use of selenium sulfide in the form of a shampoo or lotion in humans does not appear to normally increase circulating or urinary selenium levels. [79], Selenium is a catalyst in some chemical reactions, but it is not widely used because of issues with toxicity. Selenium disulfide, also known as selenious disulfide, selenous disulfide, or selenium (IV) disulfide is a chemical compound. [144] Ruminants are particularly susceptible. [5], Side effects may include hair discoloration, skin irritation, and risk of systemic absorption and toxicity, among others. Except where otherwise noted, data are given for materials in their, Risto S. Laitinen, Pentti Pekone, Yrj Hiltunen and Tapanin A. Pakkanen (1989), "The, Arto Maaninen, Tristram Chivers, Masood Parvez, Jarkko Pietikinen, and Risto S. Laitinen (1999), "Syntheses of THF Solutions of SeX, https://en.wikipedia.org/w/index.php?title=Selenium_hexasulfide&oldid=1034028012, Chemical articles with multiple compound IDs, Chemical articles with multiple PubChem CIDs, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Short description is different from Wikidata, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 17 July 2021, at 10:18. Selenium disulfide has been used in shampoo as an antidandruff agent, an inhibitor in polymer chemistry, a glass dye, and a reducing agent in fireworks. Selenium monosulfide, along with elemental selenium and sulfur, has been used in medicinal preparations in the past,[32] causing confusion and contradiction[33] as to exactly what form selenium is in any given topical preparation. 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Such cells were later used in battery-free light meters for photography. Selenium-specific supplements typically contain either 100 or 200g/serving. In the Se8 rings, the Se-Se distance varies depending on where the pair of atoms is in the ring, but the average is 233.5 pm, and the Se-Se-Se angle is on average 105.7. Selenium sulfides are a group of 8 memebered ring compounds, with the general formula Se8-n Sn. After this, the suspension may be used at less frequent intervals - weekly, every two weeks, or even every 3 or 4 weeks in some cases. Respiratory capacity is further reduced due to selenium binding to hemoglobin. Upon heating, it softens at 50C and converts to gray selenium at 180C; the transformation temperature is reduced by presence of halogens and amines. Five of these, 74Se, 76Se, 77Se, 78Se, 80Se, are stable, with 80Se being the most abundant (49.6% natural abundance). It is a nonmetal (more rarely considered a metalloid ) with properties that are intermediate between the elements above and below in the periodic table, sulfur and tellurium, and also has similarities to arsenic. ), woody asters (Xylorhiza sp. [113] Marine fishes and vertebrate thyroid glands have the highest concentration of selenium and iodine. |?Label Name [41][42] It was discovered to be essential for mammalian life in 1957. Allow product to remain on skin for 10 minutes, then rinse the body thoroughly. [137], Selenium deficiency can occur in patients with severely compromised intestinal function, those undergoing total parenteral nutrition, and[138] in those of advanced age (over 90). Selenium sulfide can refer to either of the following: Selenium disulfide, SeS 2. It is insoluble in water. Daddy Got Dick, directed by David Romero for Pantheon Productions at NakedSword gives us simply fantastic pairings of beefy masculinity. Its molecular structure consists of a ring of two selenium and six sulfur atoms, analogous to the S8 allotrope of sulfur (cyclooctasulfur) and other selenium sulfides with formula SenS8n.[2]. Allow to remain on scalp for 2 to 3 minutes. In the United States, Selenium disulfide was approved for medical use as early as 1951. DermNet provides Google Translate, a free machine translation service. they are not mapped one onto another by any symmetry operation), and in fact in the -monoclinic form, half the rings are in one configuration (and its mirror image) and half in another. Selenium sulfide appears to have a cytostatic effect on cells of the epidermis and follicular epithelium, thus reducing corneocyte production. When that doc is a hottie in cute nerd glasses continue reading, French professional tennis beaux Fabien Reboul posted a photo of he and fellow French tennis stud Maxence Broville kissing, both wearing the official outfits (kits) from the Slade Toulousain Tennis continue reading. Do not use more of it, do not use it more often, and do not use it for a longer time than recommended. [30] Both chemists owned a chemistry plant near Gripsholm, Sweden, producing sulfuric acid by the lead chamber process. However, it can damage plants at higher doses. The new brass is marketed under the name EnviroBrass. Selenium requirements in plants differ by species, with some plants requiring relatively large amounts and others apparently not requiring any. Selenium sulfide | SSe - PubChem Apologies, we are having some trouble retrieving data from our servers PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology The recoding mechanism was worked out first in bacteria and then in mammals (see SECIS element).[45]. [8], The most stable and dense form of selenium is gray and has a chiral hexagonal crystal lattice (space group 152 or 154 depending on the chirality)[12] consisting of helical polymeric chains, where the Se-Se distance is 237.3pm and Se-Se-Se angle is 103.1. Selenium has seven naturally occurring isotopes. Selenium sulfide is toxic by ingestion and inhalation, and is irritating to skin and eyes. In organic chemistry, butyl is a four-carbon alkyl radical or substituent group with general chemical formula C 4 H 9, derived from either of the two isomers (n-butane and isobutane) of butane.. Dermatology Made Easybook. By contrast, selenates and selenites have an oxidant mode of action similar to that of arsenic trioxide and are very toxic. National Research Council, Committee on Nutrient Requirements of Small Ruminants (2007). Further studies are needed to confirm these interactions. [29], Selenium (Greek selene meaning "Moon") was discovered in 1817 by Jns Jacob Berzelius and Johan Gottlieb Gahn. Repeat treatments as directed by physician. [141], Selenium interacts with other nutrients, such as iodine and vitamin E. The effect of selenium deficiency on health remains uncertain, particularly in relation to Kashin-Beck disease. [90] High selenium levels in waterways were found to cause congenital disorders in oviparous species, including wetland birds[91] and fish. [8], The red , , and forms are produced from solutions of black selenium by varying the evaporation rate of the solvent (usually CS2). In plants, it occurs as a bystander mineral,[95] sometimes in toxic proportions in forage (some plants may accumulate selenium as a defense against being eaten by animals,[96] but other plants, such as locoweed, require selenium, and their growth indicates the presence of selenium in soil).[97]. Stop using the preparation and check with your doctor if you experience scalp irritation or skin irritation. Selenium disulfide, also known as selenium sulfide, is a chemical compound and medication used to treat seborrheic dermatitis, dandruff, and pityriasis versicolor. [147] Neonate ruminants at risk of white muscle disease may be administered both selenium and vitamin E by injection; some of the WMD myopathies respond only to selenium, some only to vitamin E, and some to either. Selenium's semiconductor properties found numerous other applications in electronics. [2] Use is not recommended in children less than 25 years old. Some analytical techniques are capable of distinguishing organic from inorganic forms of the element. [148], The effects of selenium intake on cancer have been studied in several clinical trials and epidemiologic studies in humans. There is limited information regarding Nonclinical Toxicology of Selenium sulfide in the drug label. It is more acidic than H2S. It is recommended that a water concentration of 2g Se/L be considered highly hazardous to sensitive fish and aquatic birds. Selenoprotein families of GSH-Px and the deiodinases of eukaryotic cells seem to have a bacterial phylogenetic origin. WebSelsun Blue 2-in-1 Anti-dandruff Shampoo & Conditioner, 11 fl. Selenium is a chemical element with the symbol Se and atomic number 34. Jump search Mixture selenium sulfides.mw parser output .infobox subbox padding border none margin 3px width auto min width 100 font size 100 clear none float none background color |?Pill Name [133], In fish and other wildlife, selenium is necessary for life, but toxic in high doses. There is limited information regarding Drug Interaction of Selenium sulfide in the drug label. [citation needed], The deiodinase isoenzymes constitute another family of eukaryotic selenoproteins with identified enzyme function. In 1873, Willoughby Smith found that the electrical resistance of grey selenium was dependent on the ambient light. Exceeding the Tolerable Upper Intake Level of 400 micrograms per day can lead to selenosis. The 1,2 isomer can be prepared by reaction of chlorosulfanes and dichlorodiselane with potassium iodide in carbon disulfide. Should not be used when acute inflammation or exudation is present as increased absorption may occur. When applied to the body for treatment of tinea versicolor, Selenium Sulfide Topical Suspension USP, 2.5% (Lotion) may produce skin irritation especially in the genital area and where skin folds occur. There is no FDA guidance on the use of Selenium sulfide with respect to nursing mothers. [35] It has also been reported to be effective in the treatment of scalp psoriasis based on clinical observation of over 100treated patients and two case reports of dramatic response. [7][8][9], Selenium disulfide was approved for medical use in the United States at least as early as 1951. With strong reducing agents, it forms polyselenides. Many benthic invertebrates can tolerate selenium concentrations up to 300g/L of Se in their diet. Twenty male patients with a diagnosis of tinea versicolor were randomly assigned to two parallel groups who applied selenium sulfide lotion or the vehicle to the entire skin surface, excluding mucous membranes, fo SHAKE WELL BEFORE USING. [47][48] Ocean water contains significant amounts of selenium. Cookies help us deliver our services. Cancer patients receiving daily oral doses of selenothionine may achieve very high plasma and urine selenium concentrations. There is limited information regarding Off-Label NonGuideline-Supported Use of Selenium sulfide in pediatric patients. Selenium sulfide has the molecular formula SeS2 and has a molecular weight of 143.09. In some countries, higher strength preparations are only available on a doctor's prescription. There is limited information regarding Pharmacokinetics of Selenium sulfide in the drug label. Rhyheim Shabazz has raised the bar for cock-in-butt content time and time again, with next-level work that conveys the sheer and utter pleasure of sex and sensuality. Other selenium allotropes may contain Se6 or Se7 rings. Cybersocket got the dish on this stud in our latest 7 Sexy Questions continue reading, Over at Family Dick, weve previously seen a couple incarnations of the stepdad/son relationship between Derek Allen and Myott Hunter. Consistent with trends indicated by the double bond rule, selenoketones, R(C=Se)R, and selenaldehydes, R(C=Se)H, are rarely observed. The chemistry of the selenides and sulfides is similar. China is the largest consumer of selenium dioxide for this purpose. [19] Selsun Blue is an over-the-counter shampoo for dandruff with 1% selenium disulfide as its active ingredient. If sensitivity reactions occur, use should be discontinued. Selenium sulfide can be used safely on the scalp in pregnant women. [139], Selenium deficiency, defined by low (<60% of normal) selenoenzyme activity levels in brain and endocrine tissues, occurs only when a low selenium level is linked with an additional stress, such as high exposures to mercury[140] or increased oxidant stress from vitamin E deficiency. In 1954, the first hints of specific biological functions of selenium were discovered in microorganisms by biochemist, Jane Pinsent. There are, however, a few species that have been seen to survive these events and tolerate the increased selenium. The reaction produces also cyclooctaselenium Se8 and all other eight-member cyclic selenium sulfides, except SeS7, and several six- and seven-membered rings.[2]. [17] However, the review did suggest use of over-the-counter selenium disulfide shampoos as an inexpensive option for managing mild symptoms of seborrheic dermatitis. The specific chemicals contain a variable number of S and Se atoms, SenS8n. Because of its similarity to tellurium, named for the Earth, Berzelius named the new element after the Moon.[31][32]. Organoselenium compounds can be concentrated over 200,000 times by zooplankton when water concentrations are in the 0.5 to 0.8g Se/L range. [15][16] A randomized controlled trial of 100 people who received selenium disulfide reported side effects of itching or burning sensation of the scalp (3people), eruption near the hairline (1person), psoriasis (1person), lightening or bleaching of hair color (2people), orange staining of the scalp (1person), and a chemical taste while shampooing (1person). Selenium hexasulfide is a chemical compound with formula Se 2 S 6. There is limited information regarding FDA-Labeled Use of Selenium sulfide in pediatric patients. The chief commercial uses for selenium today are glassmaking and pigments. Selenium is a semiconductor and is used in photocells. Applications in electronics, once important, have been mostly replaced with silicon semiconductor devices. Selenium is still used in a few types of DC power surge protectors and one type of fluorescent quantum dot. [1][4] Use in pregnancy or breastfeeding has not been studied. There is no FDA guidance on the use of Selenium sulfide in patients with hepatic impairment. Selenium sulfide 2.5% strength is used also on the body to treat tinea versicolor (a type of fungus infection of the skin). In people prone to dandruff, an uninflamed form of seborrhoeic dermatitis, the fungus Malassezia can cause irritation, itching and increased shedding of dead skin cells in areas of the scalp. Small amounts of organoselenium compounds have been used to modify the catalysts used for the vulcanization for the production of rubber.[58]. Top 10 Uses of SeleniumAutomated testing. Earlier, people used to do manual testing which used to be a big headache. Important Benefits. Less burden and stress for testers As mentioned above, the amount of time required to do testing repeated test scenarios on each and every new build Reduction in Human resources. Several supplementary services. Fast and accurate. More items Selenium sulfide is a bright orange colored powder. At levels of 1mg/m3, selenium is immediately dangerous to life and health. Peaches and pears given a foliar selenium spray contained higher levels of selenium and also stayed firm and ripe longer when in storage. The only stable chloride is selenium monochloride (Se2Cl2), which might be better known as selenium(I) chloride; the corresponding bromide is also known. [15], A 2015 review recommended topical antifungal agents, topical corticosteroids, and topical calcineurin inhibitors like tacrolimus as the main treatments for seborrheic dermatitis based on good-quality evidence, rather than selenium disulfide for which evidence is much more limited. For this reason, evacuation of the stomach contents should be considered in cases of acute oral ingestion. [6], Selenium forms several allotropes that interconvert with temperature changes, depending somewhat on the rate of temperature change. Selenium sulfide is a antiseborrheic and dermatological agent that is FDA approved for the treatment of tinea versicolor, seborrheic dermatitis of the scalp, and dandruff. In low doses, selenium has shown a beneficial effect on plant resistance to various environmental stress factors including drought, UV-B, soil salinity, and cold or hot temperatures. In decreasing order of severity: skin irritation, occasional reports of increase in amount of normal hair loss, discoloration of hair (can be avoided or minimized by thorough rinsing of hair after treatment). The most notable exception is in power DC surge protection, where the superior energy capabilities of selenium suppressors make them more desirable than metal-oxide varistors. Massage about 1 or 2 teaspoonsful of suspension into wet scalp. Repeat this procedure once a day for seven days. A liquid antiseborrheic, antifungal preparation for topical application. WebSelenium sulfide appears to have a cytostatic effect on cells of the epidermis and follicular epithelium, reducing corneocyte production. [15][16] Based on the study, the systematic review concluded that selenium disulfide may be effective in the treatment of dandruff but that the available evidence is limited and overall evidence quality is low. 6. Selenium hexasulfide, Se 2 S 6 Index of chemical compounds with the same name This set index page lists chemical compounds articles associated with the same name. There is no FDA guidance on the use of Selenium sulfide in women of reproductive potentials and males. Commercially, selenium is produced as a byproduct in the refining of these ores, most often during production. A previous sharp increase was observed in 2004 from $4$5 to $27/lb. Instructions for use of selenium sulfide shampoo, 58292001, 768430000, 780436000, 332719006. This one does too, but it a really good way like in a two boxes of Kleenex way. Alkali metal selenides react with selenium to form polyselenides, Se2n, which exist as chains. [71] These detectors use amorphous selenium to capture and convert incident x-ray photons directly into electric charge.[72]. At low levels, it is used in the body to create anti-oxidant selenoproteins, at higher doses than normal it causes cell death. Note that this may not provide an exact translation in all languages, Home It is used to make medicated shampoos. |?Pill Color Drug Information: Selenium Sulfide (Topical), Apply enough selenium sulfide shampoo to the scalp to, Allow lather to remain on scalp for 2-3 minutes before rinsing off, Repeat with a second wash then rinse well, Use 1% or 2.5% shampoo twice a week for the first 2 weeks, then once weekly for 2, 3 or 4 weeks, and then only when necessary, Apply selenium sulfide lotion to affected areas of the body (do not apply to face or genitals), Work up a lather using a small amount of water, Allow the medicine to stay in contact with your skin for about 10 minutes, Rinse body well to remove all the medicine, Use the 2.5% lotion once per day for 7 days, Unusual oiliness or dryness of hair or scalp. |?Pill Shape Selenium from Greek seln ( 'Moon') was discovered in 1817 by Jns Jacob Berzelius, who noted the similarity of the new element to the previously discovered tellurium (named for the Earth). [108][109] It seems as though when mercury levels in a marine fish rise, so do the selenium levels. In addition to controlling the symptoms of dandruff, selenium sulfide is also used to treat pityriasis versicolor, a fungal infection of the skin and tinea captis, a fungal infection of the scalp. [61], Researchers found that application of selenium fertilizer to lettuce crops decreased the accumulation of lead and cadmium. This set index page lists chemical compounds articles These findings suggest that, with the exception of vertebrates, aquatic life supports selenium use, whereas terrestrial habitats lead to reduced use of this trace element. There is no FDA guidance on the use of Selenium sulfide with respect to specific racial populations. [46] Isolation of selenium is often complicated by the presence of other compounds and elements. The glutathione peroxidase family of enzymes (GSH-Px) catalyze certain reactions that remove reactive oxygen species such as hydrogen peroxide and organic hydroperoxides: The thyroid gland and every cell that uses thyroid hormone use selenium,[99] which is a cofactor for the three of the four known types of thyroid hormone deiodinases, which activate and then deactivate various thyroid hormones and their metabolites; the iodothyronine deiodinases are the subfamily of deiodinase enzymes that use selenium as the otherwise rare amino acid selenocysteine. Selenium poisoning can be passed from parents to offspring through the egg, and selenium poisoning may persist for many generations. [2][3]It is applied to the Reproduction of mallard ducks is impaired at dietary concentrations of 7g Se/L. Brazil nuts are the richest dietary source (though this is soil-dependent, since the Brazil nut does not require high levels of the element for its own needs).[119][120]. Especially common are selenides (R2Se, analogues of thioethers), diselenides (R2Se2, analogues of disulfides), and selenols (RSeH, analogues of thiols). Selen disulfide l mt loi thuc c s dng iu tr chng au tht ngc, vim da tit b v gu. [21] Selenium disulfide may also discolor metallic jewellery. This film features 11 of Bel Alam Wernik has become one of the most popular bottoms in current porn, rightfully so. It is also used to treat some fungal infections of the skin. [2] Selenium disulfide appears to be much less toxic than other selenium salts, which may be attributed to its low aqueous solubility and very poor systemic absorption. It is listed as an essential medicine by the World Health Organization. WikiDoc MAKES NO GUARANTEE OF VALIDITY. A group of academics, therefore, tried to use this brand of shampoo to stop an alien invasion after discovering that the alien life form was sensitive to selenium. 4.2 Potential Exposure Selenium sulfide is used for the treatment of seborrhea, especially in shampoos. {{#ask: Page Name::Selenium sulfide Selenium was the basis of the very first solar cells, with the first example of rooftop solar being a selenium cell from 1884. [17] The non-primordial radioisotope 79Se also occurs in minute quantities in uranium ores as a product of nuclear fission. [36], Selenium sulfide is under development for the treatment of meibomianitis (meibomian gland dysfunction) and dry eyes in topical and ophthalmic formulations. [47][48], In living systems, selenium is found in the amino acids selenomethionine, selenocysteine, and methylselenocysteine. WebSelenium is a chemical element with the symbol Se and atomic number 34. [106][107] An antioxidant, selenoneine, which is derived from selenium and has been found to be present in the blood of bluefin tuna, is the subject of scientific research regarding its possible roles in inflammatory and chronic diseases, methylmercury detoxification, and oxidative damages. Selenium rectifiers were first used in 1933. [51][52], Typical background concentrations of selenium do not exceed 1ng/m3 in the atmosphere; 1mg/kg in soil and vegetation and 0.5 g/L in freshwater and seawater. N c s dng cho kem dng da hoc du gi u. The selenium cell was used in the photophone developed by Alexander Graham Bell in 1879. CONTRAINDICATIONS: a antiseborrheic and dermatological agent that is FDA approved for the treatment of tinea versicolor, seborrheic dermatitis of the scalp, and dandruff. It seldom occurs in its elemental state or as pure ore compounds in the Earth's crust. Selenium is still used in a few types of DC power surge protectors and one type of fluorescent quantum dot. [82][83][84], 75Se is used as a gamma source in industrial radiography.[85]. There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Selenium sulfide in women who are pregnant. There is limited information regarding Clinical Studies of Selenium sulfide in the drug label. Another naturally occurring organoselenium compound is dimethyl selenide. Copper indium gallium selenide is a material used in solar cells. [3] It is an oxidizing agent. Sources of pollution include waste materials from certain mining, agricultural, petrochemical, and industrial manufacturing operations. Three days later, a pharmacy released a statement explaining that the horses had received an incorrect dose of one of the ingredients used in a vitamin/mineral supplement compound that had been incorrectly prepared by a compounding pharmacy. The chronic toxic dose of selenite for humans is about 2400 to 3000 micrograms of selenium per day. Selenium is bioaccumulated in aquatic habitats, which results in higher concentrations in organisms than the surrounding water. Unlike the other allotropes, it is insoluble in CS2. [33][34] This led to its use as a cell for sensing light. Further concentration through bioaccumulation occurs along the food chain, as predators consume selenium rich prey. Selenium occurs naturally in a number of inorganic forms, including selenide, selenate, and selenite, but these minerals are rare. This phenomenon was used in the design of light meters and similar devices. FDA-Labeled Indications and Dosage (Adult), FDA-Labeled Indications and Dosage (Pediatric), Females of Reproductive Potential and Males. [150], This article is about the chemical element. selenium, vanadium, magnesium, copper, and zinc, may have been lacking in some terrestrial mineral-deficient areas. |template=DrugLabelImages There is limited information regarding Pharmacodynamics of Selenium sulfide in the drug label. [35][36][37] The development of selenium rectifiers began during the early 1930s, and these replaced copper oxide rectifiers because they were more efficient. [7], Selenium disulfide has a composition that approximates to SeS2 and is sometimes called selenium sulfide. [57] This changes the availability of selenium because only a comparably small part of the selenium in the ore is leached with the copper. Although New Zealand soil has low levels of selenium, adverse health effects have not been detected in the residents. [101], Increased dietary selenium reduces the effects of mercury toxicity,[102][103][104] although it is effective only at low to modest doses of mercury. It is prepared by treating selenium with sulfuryl chloride (SO2Cl2). In nature, Selenium is usually combined with sulfide. Another selenium-bearing enzyme in some plants and in animals (thioredoxin reductase) generates reduced thioredoxin, a dithiol that serves as an electron source for peroxidases and also the important reducing enzyme ribonucleotide reductase that makes DNA precursors from RNA precursors. The consumption in 2010 was divided as follows: metallurgy 30%, glass manufacturing 30%, agriculture 10%, chemicals and pigments 10%, and electronics 10%. A reduction of 21% on TPO antibodies is reported with the dietary intake of 0.2mg of selenium. Electrolytic metal refining is particularly productive of selenium as a byproduct, obtained from the anode mud of copper refineries. Berzelius and Gahn wanted to use the pyrite and they also observed that the red precipitate gave off a smell like horseradish when burned. 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