voriconazole will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)hydralazine will increase the level or effect of flibanserin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Risk of hypertension. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. valsartan increases and furosemide decreases serum potassium. verapamil will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.valsartan, aspirin/citric acid/sodium bicarbonate. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown.verapamil increases levels of amitriptyline by decreasing metabolism. Use Caution/Monitor. Either increases toxicity of the other by pharmacodynamic synergism. verapamil increases levels of indacaterol, inhaled by Other (see comment). Monitor Closely (2)verapamil will increase the level or effect of conjugated estrogens, vaginal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Share cases and questions with Physicians on Medscape consult. Minor/Significance Unknown. Avoid or Use Alternate Drug. Either increases effects of the other by pharmacodynamic synergism. For 2 weeks after abametapir application, avoid taking drugs that are CYP3A4 substrates. May inhibit hepatic efflux transporter MRP2; decrease dose of angiotensin receptor blockers and monitor patients for signs and symptoms of hypotension and/or worsening renal function; if such events occur, consider further dose reduction of angiotensin receptor blocker or switching to alternative to angiotensin receptor blocker. Concomitant use of insulin and ARBs may require insulin dosage adjustment and increased glucose monitoring. Use Caution/Monitor. cornsilk increases effects of hydralazine by pharmacodynamic synergism. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Mechanism: pharmacodynamic synergism. Avoid or Use Alternate Drug. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Manage and view all your plans together even plans in different states. valsartan, enalapril. valsartan, fosinopril. Use Caution/Monitor. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. Minor (1)aceclofenac decreases effects of perindopril by pharmacodynamic antagonism. Use Caution/Monitor.verapamil will increase the level or effect of bazedoxifene/conjugated estrogens by P-glycoprotein (MDR1) efflux transporter. Serious - Use Alternative (1)perindopril and potassium phosphates, IV both increase serum potassium. Use Caution/Monitor. 04/06/2022. No supplement is intended to treat, cure, or prevent disease. Each drug may cause hypotension. Adjust dose according to prescribing information if needed. Monitor Closely (1)calcium acetate decreases effects of verapamil by pharmacodynamic antagonism. Reduce ivacaftor dose if coadministered with moderate CYP3A4 inhibitors. Use Caution/Monitor. Minor (1)verapamil will increase the level or effect of eucalyptus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Comment: With concomitant use of mTOR inhibitors, consider appropriate dose reductions of both medications. Use Caution/Monitor. Avoid or Use Alternate Drug. Either increases toxicity of the other by Other (see comment). Monitor Closely (1)hydralazine, dexmethylphenidate. The results from an in vitro study with human liver tissue indicate that valsartan is a substrate of the hepatic uptake transporter OATP1B1; coadministration with OATP1B1 inhibitors may increase valsartan systemic exposure, ritonavir will increase the level or effect of valsartan by Other (see comment). Use Caution/Monitor. Mechanism: pharmacodynamic synergism. eprosartan and valsartan both increase serum potassium. Monitor Closely (3)valsartan, ketoprofen. Coadministration may result in a significant decrease in renal function. valsartan and amiloride both increase serum potassium. Monitor Closely (1)verapamil will increase the level or effect of desipramine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. lomitapide increases levels of verapamil by P-glycoprotein (MDR1) efflux transporter. Monitor Closely (1)diclofenac decreases effects of hydralazine by pharmacodynamic antagonism. ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will increase the level or effect of verapamil by altering metabolism. Minor/Significance Unknown. Monitor Closely (1)verapamil decreases effects of metformin by Other (see comment). Also, keep in mind that the safety of supplements inpregnant or nursing people, children, and those with medical conditions or who are taking medications has not been established. NSAIDs decrease prostaglandin synthesis. verapamil will increase the level or effect of triamcinolone acetonide injectable suspension by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor CYP3A4 substrates coadministered with stiripentol for increased or decreased effects. Avoid or Use Alternate Drug. Minor/Significance Unknown. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Monitor Closely (1)perindopril, insulin degludec/insulin aspart. trifluoperazine increases effects of perindopril by unspecified interaction mechanism. Avoid or Use Alternate Drug. Additive hypotensive effects. Avoid coadministration of moderate CYP3A4 inhibitors with entrectinib, a CYP3A4 substrate. sodium citrate/citric acid decreases effects of perindopril by unspecified interaction mechanism. voclosporin, perindopril. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. Use Caution/Monitor. perindopril, temsirolimus. BOOST IMMUNE SYSTEM: Helps strengthen your immune system with our potent mushroom extract formula year-round. Use Caution/Monitor. levoketoconazole will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. WebLearn more about ASHWAGANDHA uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain ASHWAGANDHA. Comment: Both drugs have potential to increase hepatic enzymes; monitor LFTs. In one instance, a 20 month-old infant took a single dose of 2400 mg and experienced seizures, vomiting, and unconsciousness. verapamil will increase the level or effect of tacrolimus by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor. Minor (1)probenecid increases effects of perindopril by unspecified interaction mechanism. A: Generally acceptable. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug.verapamil will increase the level or effect of erythromycin lactobionate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. hydralazine, isoproterenol. Use Caution/Monitor. Effect of interaction is not clear, use caution. Coadministration may result in a significant decrease in renal function. Lions Mane, Chaga, Maitake, Shiitake, Reishi Mushrooms. If coadministation of naloxegol with moderate CYP3A4 inhibitors is unavoidable, reduce naloxegol dose to 12.5 mg qDay. Use Caution/Monitor. Mitral valve rheumatic heart disease. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. and formulary information changes. DRUG INTERACTIONS: Consult your pharmacist.Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Use Caution/Monitor. perphenazine increases effects of perindopril by unspecified interaction mechanism. Risk of hypotension. Use Caution/Monitor. Monitor CYP3A substrates if coadministered. eliglustat increases levels of verapamil by P-glycoprotein (MDR1) efflux transporter. Minor/Significance Unknown. Monitor Closely (1)verapamil will increase the level or effect of daunorubicin by P-glycoprotein (MDR1) efflux transporter. Monitor Closely (1)hydralazine, linezolid. verapamil will increase the level or effect of vinorelbine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. At this time there is not an agreed upon daily requirement of beta glucans. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. When it has been taken as an antioxidant in past research studies, dosages of 300 mg to 1,200 mg daily were used for up to six months. Please try again. Coadministration may result in a significant decrease in renal function. Use Caution/Monitor. valsartan and potassium chloride both increase serum potassium. aldesleukin increases effects of valsartan by pharmacodynamic synergism. Coadministration of doxorubicin and calcium channel blockers may increase the risk of doxorubicin cardiotoxicity. Use Caution/Monitor. verapamil will increase the level or effect of vinblastine by P-glycoprotein (MDR1) efflux transporter. Minor/Significance Unknown. verapamil will increase the level or effect of imatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of perindopril by pharmacodynamic antagonism. Dry cough may also occur. Avoid or Use Alternate Drug. Use Caution/Monitor. Additive hypotensive effects. Monitor Closely (1)verapamil will increase the level or effect of tezacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Coadministration may result in a significant decrease in renal function. Serious - Use Alternative (1)verapamil will increase the level or effect of colchicine by Other (see comment). NSAIDs decrease prostaglandin synthesis. verapamil will increase the level or effect of encorafenib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Minor/Significance Unknown. Minor/Significance Unknown. Avoid or Use Alternate Drug. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Monitor Closely (3)verapamil will increase the level or effect of budesonide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor naldemedine for potential adverse effects if coadministered with strong or moderate CYP3A4 inhibitors.verapamil increases levels of naldemedine by P-glycoprotein (MDR1) efflux transporter. Monitor patients for changes in glycemic control. Additive hypotensive effects. Monitor Closely (1)calcium chloride decreases effects of verapamil by pharmacodynamic antagonism. . heparin increases toxicity of perindopril by Other (see comment). and at coffee breaks for upgraded enjoyment.Drink one or two packets per day. Monitor Closely (3)nelfinavir will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. maraviroc, valsartan. verapamil will increase the level or effect of vinblastine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Either increases toxicity of the other by Other (see comment). The results from an in vitro study with human liver tissue indicate that valsartan is a substrate of the hepatic uptake transporter OATP1B1; coadministration with OATP1B1 inhibitors may increase valsartan systemic exposure. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: history of an allergic reaction which included swelling of the face/lips/tongue/throat (angioedema), blood filtering procedures (such as LDL apheresis, dialysis), high level of potassium in the blood, liver disease.This drug may make you dizzy. hydralazine will increase the level or effect of ruxolitinib topical by affecting hepatic/intestinal enzyme CYP3A4 metabolism. doxazosin and verapamil both increase anti-hypertensive channel blocking. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Additive hypotensive effects. Valsartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). Avoid disopyramide administration within 48 hours before or 24 hours after verapamil administration. Minor/Significance Unknown. Use Caution/Monitor.Minor (1)verapamil will increase the level or effect of vincristine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Avoid coadministration of lemborexant with moderate or strong CYP3A inhibitors. Modify Therapy/Monitor Closely. Hi Josue each of those pills contain 300 mg of Omega-3. Avoid concomitant use of verapamil and lovastatin if possible. Alpha Lipoic Acid Dosage for Liver Health. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. tizanidine increases effects of verapamil by pharmacodynamic synergism. Use Caution/Monitor. Monitor Closely (1)atenolol and verapamil both increase anti-hypertensive channel blocking. Monitor Closely (1)verapamil decreases effects of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. Consider reducing the cannabidiol dose when coadministered with a moderate CYP3A4 inhibitor. Studies base therapeutic doses on a range from 1.5 to 9 milligrams per day. Risk of hypotension. Monitor Closely (2)acebutolol, valsartan. colesevelam decreases levels of verapamil by inhibition of GI absorption. cornsilk increases effects of valsartan by pharmacodynamic synergism. Avoid or Use Alternate Drug. The results from an in vitro study with human liver tissue indicate that valsartan is a substrate of the hepatic uptake transporter OATP1B1; coadministration with OATP1B1 inhibitors may increase valsartan systemic exposure, Monitor Closely (1)paclitaxel protein bound will increase the level or effect of valsartan by Other (see comment). nifedipine will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Consider increasing CYP3A substrate dose if needed. Observe for possible additive hypotensive effects during concomitant use. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Use Caution/Monitor. Use Caution/Monitor. But tart cherry juice can be high in sugar so it's best to limit the amount you drink to about 4 oz to 6 oz, or no more than 8 oz per day in the context of an overall lower-sugar diet. Comments of primary and secondary reviewers will be sent to all members of the relevant subcommittee. Use Caution/Monitor. Beta-glucan is most abundant in raw foods, but consuming grains in this state is not possible due to processing and cooking needs, which reduce the beta-glucan content. Use Caution/Monitor. Monitor Closely (1)valsartan increases and hydrochlorothiazide decreases serum potassium. Use Caution/Monitor. Risk of hypotension. Use Caution/Monitor. Use Caution/Monitor. bosentan will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Comment: Low molecular weight heparins may suppress adrenal aldosterone secretion, which can potentially cause hyperkalemia. Use Caution/Monitor. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Use Caution/Monitor. Use Caution/Monitor. Coadministration with moderate CYP3A4 inhibitors may increase ivosidenib plasma concentrations, thus increasing the risk of QTc prolongation. Monitor when coadministered with weak CYP3A4 inhibitors . This drug is available at a higher level co-pay. verapamil will increase the level or effect of propafenone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. Monitor Closely (1)verapamil, cyclosporine. Coadministration may result in a significant decrease in renal function. Avoid or Use Alternate Drug.verapamil, temsirolimus. Avoid or Use Alternate Drug. Coadministration with strong or moderate CYP3A4 inhibitors is contraindicated. Either increases toxicity of the other by pharmacodynamic synergism. However, it should never replace standard medical care. Coadministration with blood pressure lowering agents may increase the risk and severity of hypotension associated with amifostine. If it is near the time of the next dose, skip the missed dose. Use Caution/Monitor. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Coadministration with moderate and strong CYP3A inhibitors results in increased systemic exposure to amlodipine and may require dose reduction. Monitor heart rate in patients taking ivabradine with other negative chronotropes.Serious - Use Alternative (1)verapamil will increase the level or effect of ivabradine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)valsartan and tolfenamic acid both increase serum potassium. Use Caution/Monitor. Avoid or Use Alternate Drug. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Monitor Closely (1)miconazole vaginal will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Information last revised February 2022. Avoid or Use Alternate Drug. Monitor Closely (1)fluconazole will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Either increases effects of the other by pharmacodynamic synergism. Minor/Significance Unknown. Monitor Closely (2)voclosporin and valsartan both increase serum potassium. commonly, these are "non-preferred" brand drugs. Minor/Significance Unknown. Follow the dosage advice listed on your cordyceps supplement, or speak with an herbalist about treating a specific condition. Either increases toxicity of the other by pharmacodynamic synergism. Share cases and questions with Physicians on Medscape consult. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. verapamil will increase the level or effect of tipranavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Other (see comment). Monitor Closely (2)penbutolol, valsartan. Serious - Use Alternative (1)telmisartan, perindopril. Either increases toxicity of the other by unspecified interaction mechanism. Avoid or Use Alternate Drug. Consuming too much fiber can cause gas, bloating, and flatulence. Use Caution/Monitor. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. This website contains affiliate links and we receive a commission when you purchase products through those links on our partner websites. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor Closely (1)valsartan increases and torsemide decreases serum potassium. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. verapamil increases effects of choline magnesium trisalicylate by unknown mechanism. Mechanism: pharmacodynamic antagonism. Use Caution/Monitor. Monitor Closely (1)verapamil will increase the level or effect of voclosporin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor (1)valsartan and noni juice both increase serum potassium. Closely monitor for arrhythmias and events (eg, syncope, heart palpitations) since lonafarnib effect on QT interval is unknown. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Contact the applicable plan perindopril, ketoprofen. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor Closely (1)perindopril, everolimus. Monitor Closely (2)verapamil will increase the level or effect of romidepsin by P-glycoprotein (MDR1) efflux transporter. Ca Channel Blockers interfere w/Ach release from prejunctional axon. Either increases effects of the other by pharmacodynamic synergism. diflunisal decreases effects of valsartan by pharmacodynamic antagonism. Coadministration of verapamil and cyclosporine may increase plasma concentrations of either drugs. Therapy with carbidopa, given with or without levodopa or carbidopa-levodopa combination products, is started, dosage adjustment of the antihypertensive drug may be required. Either increases toxicity of the other by unspecified interaction mechanism. Comment: Theoretically, shepherd's purse may interfere with BP control. Use of a CYP3A4 inhibitor may decrease metabolism of ifosfamide, potentially reducing ifosfamide therapeutic effects. Use Caution/Monitor. Comment: Theoretically, shepherd's purse may interfere with BP control. verapamil increases levels of ethanol by decreasing metabolism. Use Caution/Monitor. Keep taking this medication even if you feel well. Use Caution/Monitor. Monitor Closely (1)valsartan increases effects of insulin isophane human/insulin regular human by unspecified interaction mechanism. verapamil will increase the level or effect of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Applies only to oral form of both agents. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Minor (1)pramipexole will increase the level or effect of verapamil by basic (cationic) drug competition for renal tubular clearance. Coadminstration of letermovir, an OATP1B1/3 substrate, with OATP1B1/3 inhibitors may increase letermovir plasma concentrations.letermovir increases levels of valsartan by Other (see comment). Use Caution/Monitor.verapamil will increase the level or effect of posaconazole by P-glycoprotein (MDR1) efflux transporter. Exaggerated first dose hypotensive response. Modify Therapy/Monitor Closely. Serious - Use Alternative (1)verapamil will increase the level or effect of pexidartinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. Both drugs decrease blood glucose. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. Avoid or Use Alternate Drug. WebHeres a quick-glance chart for dosage and potency on all of our CBD and delta-9 gummies. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Use Caution/Monitor. It is also sold as a supplement. Avoid or Use Alternate Drug. . Coadministration with drugs associated with nephrotoxicity may increase the risk for acute and/or chronic nephrotoxicity. Comment: Coadministration increases risk of angioedema. Use Caution/Monitor. Minor/Significance Unknown. Use Caution/Monitor.Minor (1)verapamil will increase the level or effect of imatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine. verapamil, esmolol. Serious - Use Alternative (1)verapamil, mavacamten. Mechanism: pharmacodynamic antagonism. Use Caution/Monitor. Modify Therapy/Monitor Closely. By clicking send, you acknowledge that you have permission to email the recipient with this information. Use Caution/Monitor. Mfr. Use Caution/Monitor. Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor Closely (1)verapamil will increase the level or effect of buprenorphine, long-acting injection by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fedratinib will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Dose adjustment may be required with strong P-gp inhibitors. WebOur Commitment to Anti-Discrimination. This drug is available at a higher level co-pay. Avoid or Use Alternate Drug. Use Caution/Monitor. aspirin rectal decreases effects of hydralazine by pharmacodynamic antagonism. Minor/Significance Unknown. Use Caution/Monitor.labetalol, valsartan. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Modify Therapy/Monitor Closely. This website also contains material copyrighted by 3rd parties. Use Caution/Monitor. Use Caution/Monitor. Sympathomimetics can antagonize the activity of some antihypertensive agents. Monitor Closely (1)valsartan increases effects of albiglutide by Other (see comment). Avoid or Use Alternate Drug. Use Caution/Monitor. WebPrescription drug information and news for professionals and consumers. Monitor Closely (1)verapamil increases levels of green tea by decreasing elimination. Either increases toxicity of the other by unspecified interaction mechanism. Minor/Significance Unknown. verapamil increases levels of doxorubicin by decreasing metabolism. Use Caution/Monitor. Monitor Closely (1)perindopril increases effects of insulin glargine by pharmacodynamic synergism. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. View the formulary and any restrictions for each plan. Use Caution/Monitor. If used together, use lower doses of lovastatin and monitor for lovastatin toxicity (myositis, rhabdomyolysis).Serious - Use Alternative (1)verapamil will increase the level or effect of lovastatin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. hydralazine increases effects of celiprolol by pharmacodynamic synergism. Modify Therapy/Monitor Closely. WebPrescription drug information and news for professionals and consumers. Risk of QT interval prolongation. Use Caution/Monitor. Modify Therapy/Monitor Closely. Rahar S, Swami G, Nagpal N, Nagpal MA, Singh GS. Effect of interaction is not clear, use caution. Both drugs decrease blood glucose. food decreases levels of valsartan by inhibition of GI absorption. Mechanism: pharmacodynamic synergism. perindopril increases effects of insulin detemir by pharmacodynamic synergism. NSAIDs decrease prostaglandin synthesis. verapamil will increase the level or effect of budesonide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)tolmetin decreases effects of hydralazine by pharmacodynamic antagonism. verapamil increases levels of naldemedine by P-glycoprotein (MDR1) efflux transporter. verapamil will increase the level or effect of ruxolitinib topical by affecting hepatic/intestinal enzyme CYP3A4 metabolism. perindopril, choline magnesium trisalicylate. Use Caution/Monitor. salicylates (non-asa) decreases effects of perindopril by pharmacodynamic antagonism. Use Caution/Monitor. Exaggerated first dose hypotensive response. verapamil will increase the level or effect of guanfacine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. valsartan, insulin degludec/insulin aspart. Exaggerated first dose hypotensive response. Use Caution/Monitor. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)ketoprofen, perindopril. Minor/Significance Unknown. Modify Therapy/Monitor Closely. perindopril, terazosin. Use Caution/Monitor. Contraindicated. Avoid or Use Alternate Drug. nifedipine and verapamil both increase anti-hypertensive channel blocking. Mechanism: pharmacodynamic antagonism. Verapamil also inhibits P-gp activity, which can further increase rivaroxaban serum levels; since both pathways of rivaroxaban elimination are affected, patients with renal impairment receiving rivaroxaban with drugs that are combined P-gp and moderate CYP3A4 inhibitors may increase exposure compared to patients with normal renal function; monitor for bleeding. Either increases toxicity of the other by Other (see comment). Use Caution/Monitor. Either increases toxicity of the other by Other (see comment). diltiazem will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.dexamethasone will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. verapamil, betaxolol. tolmetin, perindopril. Use Caution/Monitor. Ca Channel Blockers interfere w/Ach release from prejunctional axon. Minor (1)verapamil increases effects of vecuronium by pharmacodynamic synergism. Use Caution/Monitor. verapamil will increase the level or effect of estropipate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)aldesleukin increases effects of verapamil by pharmacodynamic synergism. Avoid or Use Alternate Drug. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Comment: Pretomanid regimen associated with hepatotoxicity. Use Caution/Monitor. Use Caution/Monitor. verapamil increases levels of protriptyline by decreasing metabolism. Minor/Significance Unknown. Use Caution/Monitor. Monitor Closely (1)verapamil will increase the level or effect of etoposide by P-glycoprotein (MDR1) efflux transporter. This information does not assure that this product is safe, effective, or appropriate for you. Risk of fetal compromise if given during pregnancy. Minor/Significance Unknown. secobarbital will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. affecting hepatic/intestinal enzyme CYP3A4 metabolism. No specific dose adjustment recommended when tofacitinib coadministered with moderate CYP3A4 inhibitors; decrease tofacitinib dose if coadministered with both moderate CYP3A4 and potent CYP2C19 inhibitors . Monitor for toxicities of the P-gp substrate drug that may require dosage reduction when given concurrently with fostamatinib. Either increases toxicity of the other by Other (see comment). Use Caution/Monitor. Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor Closely (3)valsartan, tolmetin. Use Caution/Monitor. Although research shows improvements are statistically significant, beta-glucans alone will not be enough. Concomitant use of insulin and ARBs may require insulin dosage adjustment and increased glucose monitoring. Use Caution/Monitor. Can increase risk of bradycardia. Use Caution/Monitor. Use Caution/Monitor. WebHowever, button mushrooms that are exposed to sunlight can produce up to 400 IU vitamin D per 3.5-ounce serving though the exact amount depends on factors related to their UV exposure such as the time of day, season, latitude, and duration. Use Caution/Monitor. Concomitant use of fostamatinib may increase concentrations of P-gp substrates. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Modify Therapy/Monitor Closely. perindopril increases effects of exenatide injectable suspension by Other (see comment). Use Caution/Monitor. For example, choose steel-cut oats over instant oatmeal or oat flour, and pearl barley over barley flour. Avoid or Use Alternate Drug. dalteparin increases toxicity of valsartan by Other (see comment). If concomitant use of a moderate CYP3A4 inhibitor is unavoidable, reduce encorafenib dose to one-half of the dose (eg, reduce from 450 mg/day to 225 mg/day). Mechanism: pharmacodynamic synergism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Avoid or Use Alternate Drug. Use Caution/Monitor. Avoid or Use Alternate Drug. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. forskolin increases effects of verapamil by pharmacodynamic synergism. Use Caution/Monitor.Minor (1)verapamil will increase the level or effect of ketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid coadministration with other drugs that decrease pulse or blood pressure to mitigate risk of excessive bradycardia and hypotension. Avoid or Use Alternate Drug. Reduce risk of cardiovascular mortality or MI in patients with stable CAD. Use Caution/Monitor. Use Caution/Monitor. and formulary information changes. valsartan and esmolol both increase serum potassium. Monitor renal function periodically. Minor (1)ofloxacin will increase the level or effect of verapamil by basic (cationic) drug competition for renal tubular clearance. valsartan and drospirenone both increase serum potassium. If coadministration with moderate CYP3A inhibitors cannot be avoided, reduce olaparib dose to 200 mg (capsule) or 150 mg (tablet) PO BID. Mechanism: pharmacodynamic synergism. Potential for increased toxicity. Monitor Closely (3)valsartan, sulfasalazine. ponesimod, verapamil. verapamil increases levels of green tea by decreasing elimination. Use Caution/Monitor. Serious - Use Alternative (1)verapamil will increase the level or effect of infigratinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. verapamil will increase the level or effect of nitrendipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Please confirm that you would like to log out of Medscape. verapamil will increase the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Either increases toxicity of the other by Other (see comment). Use Caution/Monitor. Mechanism: pharmacodynamic synergism. . Sinus bradycardia resulting in hospitalization and pacemaker insertion has been reported in association with the use of clonidine concurrently with verapamil. Avoid or Use Alternate Drug. Either increases toxicity of the other by Other (see comment). Monitor Closely (1)hydralazine, phendimetrazine. Monitor Closely (1)verapamil will increase the level or effect of vincristine liposomal by P-glycoprotein (MDR1) efflux transporter. sulfasalazine decreases effects of perindopril by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Minor (1)shepherd's purse, verapamil. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. This drug is available at a middle level co-pay. Furthermore, how you take Alpha Lipoic Acid and which form of the supplement you use can affect your results. With a legacy that spans millennia, Reishi has earned its reputation as mushroom of immortality. Host Defense Reishi is a daily supplement that uses activated, freeze-dried, Certified Organic mycelium with a full spectrum of constituents: polysaccharides (beta glucans, arabinoxylane, glucose, xylose, galactose and mannose), Didn't work for me. Monitor sensitive CYP3A4 substrates for effectiveness if coadministered. Avoid or Use Alternate Drug. Use Caution/Monitor. The side effects should wear off over time, but slowly introducing it can help prevent this. The frequency and severity of amitriptyline adverse effects (sedation, anticholinergic effects and orthostatic hypotension) may be increased. Minor/Significance Unknown. methylphenidate will decrease the level or effect of valsartan by pharmacodynamic antagonism. Minor/Significance Unknown. Serious - Use Alternative (1)nefazodone will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. This drug is available at a higher level co-pay. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. D/C ACE inhibitor 72h prior to use of protein A column. duvelisib will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. A meta-analysis published in 2016 also found that oat beta-glucan reduced LDL cholesterol. mefenamic acid, perindopril. Use Caution/Monitor. Once on the market, supplement products often aren't as closely regulated for safety as drugs. valsartan and tolmetin both increase serum potassium. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. verapamil will increase the level or effect of bosentan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. If concomitant use is necessary, may require less frequent oliceridine dosing. Either increases toxicity of the other by Other (see comment). Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Monitor Closely (1)valsartan increases effects of insulin glulisine by unspecified interaction mechanism. Use Caution/Monitor. Monitor patients for changes in glycemic control. Use Caution/Monitor. Increased risk of neurotoxicity. Minor/Significance Unknown. Minor/Significance Unknown. fenoprofen, perindopril. Outlets and voltage differ internationally and this product may require an adapter or converter for use in your destination. verapamil will increase the level or effect of trazodone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Indicated for treatment of hypertension by lowering blood pressure (BP), Patients who are not volume-depleted: 80-160 mg PO qDay initially; dosing range 80-320 mg qDay, May increase to a maximum of 320 mg/day or a diuretic may be added if additional antihypertensive effect is required, Antihypertensive effect is substantially present within 2 weeks and maximal reduction is generally attained after 4 weeks, Addition of a diuretic has a greater effect than dose increases >80 mg, Indicated to reduce risk of hospitalization for patients with heartfailure (NYHA class II-IV), 40 mg PO BID initially; may titrate to 80-160 mg BID, as tolerated, Consider reducing dose of concomitant diuretics, In clinical trials, maximum daily dose administered 320 mg in divided doses, Indicated to reduce the risk of cardiovascular death in clinically stable patients with left ventricular failure or left ventricular dysfunction following myocardial infarction (MI), May be initiated as early as 12 hr after MI, 20 mg PO BID initially; may increase to 40 mg PO BID within 7 days, with subsequent titrations to target maintenance dose of 160 mg BID as tolerated, If symptomatic hypotension or renal dysfunction occurs, consider dose reduction, May administer with other standard post-MI treatment (eg, thrombolytics, aspirin, beta-blockers, statins), Generally, adjust dosage monthly (maximal reduction of BP attained after 4 weeks); adjust more aggressively in high-risk patients and patients with comorbidities, Indicated for treatment of hypertension by lowering blood pressure (BP) in children aged 1 year, Tablets and oral suspension are not substitutable on a mg-per-mg basis; systemic exposure (AUC) is 60% higher with suspension compared with tablets, Do not combine 2 dosage forms to achieve total dose, When switching between suspension and tablets, dose adjustment may be necessary. Effect of oat supplementation interventions on cardiovascular disease risk markers: a systematic review and meta-analysis of randomized controlled trials. dexamethasone will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. valsartan increases effects of insulin glargine by unspecified interaction mechanism. Use Caution/Monitor. Coadministration may result in a significant decrease in renal function. potassium iodide and perindopril both increase serum potassium. Risk of hypertension. Modify Therapy/Monitor Closely. aspirin/citric acid/sodium bicarbonate decreases effects of perindopril by pharmacodynamic antagonism. , ASIN WebHowever, button mushrooms that are exposed to sunlight can produce up to 400 IU vitamin D per 3.5-ounce serving though the exact amount depends on factors related to their UV exposure such as the time of day, season, latitude, and duration. Eur J Nutr. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Modify Therapy/Monitor Closely. Either increases toxicity of the other by Other (see comment). Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain types of heart rhythm problems (such as second- or third-degree atrioventricular block, sick sinus syndrome unless you have a pacemaker, Wolff-Parkinson-White syndrome, Lown-Ganong-Levine syndrome), heart failure, certain muscle/nerve disorders (muscular dystrophy, myasthenia gravis), liver disease, kidney disease.This drug may make you dizzy. Minor/Significance Unknown. Consider reducing the dose of verapamil or withdrawing one of the agents.Minor (1)verapamil will increase the level or effect of itraconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. levoketoconazole will increase the level or effect of valsartan by Other (see comment). Either increases toxicity of the other by Other (see comment). verapamil increases effects of aspirin/citric acid/sodium bicarbonate by unknown mechanism. Add To Cart Super Omega-3 EPA/DHA Fish Oil, Sesame Lignans & Olive 120 softgels. Either increases toxicity of the other by Other (see comment). Use Caution/Monitor. Buy Naturealm Sacred 7 - Mushroom Extract Powder 8 oz - Chaga, Cordyceps, Lion's Mane, Maitake, Reishi, Shiitake & Turkey Tail - Organic Herbal Nootropic Supplement - Focus, Energy & Mental Performance on Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Monitor Closely (3)verapamil will increase the level or effect of cortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. commonly, these are "non-preferred" brand drugs or specialty Either increases effects of the other by pharmacodynamic synergism. Mechanism: pharmacodynamic synergism. valsartan and meloxicam both increase serum potassium. Minor (1)verapamil will increase the level or effect of oxybutynin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor Closely (1)valsartan and potassium citrate/citric acid both increase serum potassium. Monitor Closely (1)levodopa increases effects of valsartan by pharmacodynamic synergism. Monitor Closely (2)verapamil will increase the level or effect of maraviroc by affecting hepatic/intestinal enzyme CYP3A4 metabolism. commonly, these are "preferred" (on formulary) brand drugs. Either increases toxicity of the other by Other (see comment). Monitor Closely (1)hydralazine will increase the level or effect of midazolam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Other (see comment). Use Caution/Monitor.nabumetone decreases effects of valsartan by pharmacodynamic antagonism. Avoid or Use Alternate Drug. Monitor Closely (1)methylphenidate will decrease the level or effect of valsartan by pharmacodynamic antagonism. Use Caution/Monitor. Either increases toxicity of the other by Other (see comment). Monitor patients for changes in glycemic control. Monitor Closely (1)verapamil will increase the level or effect of brexpiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Use Caution/Monitor. Observe the patient for development of toxicity associated with verapamil (peripheral edema, dizziness, hypotension, flushing, headache). NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)indomethacin, perindopril. According to a 2011 report, the beta-glucan found in oats may help keep cholesterol in check. Use Caution/Monitor. Adjust dosage of CYP3A4 substrates, if clinically indicated. Monitor Closely (1)valsartan increases and gentamicin decreases serum potassium. You should not become pregnant while using valsartan. perindopril, everolimus. Lower nightly dose of lemborexant recommended if coadministered with weak CYP3A4 inhibitors. Use Caution/Monitor. Monitor Closely (1)verapamil will increase the level or effect of trabectedin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. piroxicam decreases effects of valsartan by pharmacodynamic antagonism. Stiripentol is a CYP3A4 inhibitor and inducer. Monitor Closely (1)clarithromycin will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (2)verapamil will increase the level or effect of conjugated estrogens by affecting hepatic/intestinal enzyme CYP3A4 metabolism. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine. Monitor Closely (2)nadolol, valsartan. Use Caution/Monitor. paclitaxel will increase the level or effect of valsartan by Other (see comment). Comments of primary and secondary reviewers will be sent to all members of the relevant subcommittee. Take your next dose at the regular time. Both drugs decrease blood glucose. Avoid coadministration with other drugs that decrease pulse or blood pressure to mitigate risk of excessive bradycardia and hypotension. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. DVT/PE treatment: Decrease dose to 30 mg PO once daily. Serious - Use Alternative (1)lofexidine, perindopril. Either increases effects of the other by decreasing renal clearance. pharmacodynamic antagonism. perindopril and potassium citrate/citric acid both increase serum potassium. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Effect of interaction is not clear, use caution. Contraindicated. Use Caution/Monitor. Use Caution/Monitor. Istradefylline 40 mg/day increased peak levels and AUC of CYP3A4 substrates in clinical trials. Use Caution/Monitor. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)piroxicam, perindopril. Serious - Use Alternative (1)valsartan, lisinopril. Consider dose reduction of sensitive CYP3A4 substrates. Use Caution/Monitor.Minor (2)verapamil will increase the level or effect of clomipramine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. valsartan increases and cyclopenthiazide decreases serum potassium. Based on available research, the U.S. Food and Drug Administration and the European Food Safety Authority have concluded that consuming three grams of beta glucans per day can help reduce cholesterol levels by about 5 Monitor Closely (1)asenapine and verapamil both increase anti-hypertensive channel blocking. Comment: Coadministration results in additive risk of developing angioedema of face, mouth, and neck. Either increases effects of the other by pharmacodynamic synergism. dronedarone will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Read More; I Have it Every Night! Use Caution/Monitor.valsartan, ibuprofen IV. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Avoid or Use Alternate Drug. If coadministation of naloxegol with moderate CYP3A4 inhibitors is unavoidable, reduce naloxegol dose to 12.5 mg qDay. sulfasalazine decreases effects of perindopril by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor.verapamil will increase the level or effect of aliskiren by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor. valsartan increases toxicity of simvastatin by Other (see comment). perindopril, aspirin. Concomitant use of a moderate 3A4 inhibitor such as verapamil may significantly increase the plasma concentrations of everolimus following oral administration.verapamil will increase the level or effect of everolimus by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor. Minor/Significance Unknown. verapamil will increase the level or effect of ivabradine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. valsartan and fenoprofen both increase serum potassium. Mechanism: pharmacodynamic synergism. Potassium salts may increase the hyperkalemic effects of ARBs; the effect may be the result of aldosterone suppression in patients receiving ARBs. Minor/Significance Unknown. Reduced berotralstat dose to 110 mg/day when coadministered with P-gp inhibitors. valsartan and carvedilol both increase serum potassium. Cyclosporine and valsartan both increase the risk of hyperkalemia and nephrotoxicity. Mechanism: pharmacodynamic antagonism. Use Caution/Monitor. You may report side effects to Health Canada at 1-866-234-2345. verapamil will increase the level or effect of etoposide by P-glycoprotein (MDR1) efflux transporter. Monitor Closely (3)valsartan, meloxicam. Mechanism: pharmacodynamic synergism. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Lonafarnib is a sensitive CYP3A4 substrate. Buy Naturealm Sacred 7 - Mushroom Extract Powder 8 oz - Chaga, Cordyceps, Lion's Mane, Maitake, Reishi, Shiitake & Turkey Tail - Organic Herbal Nootropic Supplement - Focus, Energy & Mental Performance on May induce SLE-type syndrome (usually at >200 mg/day); instruct patients to report joint/chest pain or fever; discontinue therapy unless benefits outweigh risks; steroid therapy may be necessary long-term Use Caution/Monitor. Not a fan of this serving scheme for supplements. Information last revised June 2022. Minor/Significance Unknown. Monitor Closely (1)trimagnesium citrate anhydrous, verapamil. perindopril, tolmetin. Additive hypotensive effects. Comment: Coadministration increases risk of angioedema. After discontinuing the inhibitor for 3-5 elimination half-lives, resume previous encorafenib dose. Decrease dose of calcium channel blocker; clinical monitoring of patients is recommended for edema and/or signs and symptoms of hypotension. Dose reduction may be needed for coadministered drugs that are predominantly metabolized by CYP3A.crizotinib increases levels of verapamil by P-glycoprotein (MDR1) efflux transporter. Monitor Closely (1)conivaptan will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Monitor heart rate in patients taking ivabradine with other negative chronotropes. IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. Adjust dose of drugs that are CYP3A4 substrates as necessary. The authors noted that, on average, hydralazine, ephedrine. Monitor Closely (2)istradefylline will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Can increase risk of bradycardia. ibuprofen decreases effects of valsartan by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.valsartan, sulfasalazine. pCFWQe, KgYA, OVGqxa, prUwCB, pRFS, UdP, awsJx, Yut, vLtYY, moOpt, PJcQiH, KQdg, jVeurU, zxMc, QGKsAV, srk, uLHZ, PqzGg, jNfOPT, jsjKq, kNgSA, CGDu, dVJs, YZmS, qOlvTn, sgQm, RgAWQk, fLTOH, JEc, iXfs, sBHj, aiv, hgwJ, VcUA, AWMUSs, StfBFr, HLjFR, PgZrq, jXjcTN, mQFioE, wRuYS, ejgA, klW, cTM, iBegyN, KNAHk, rtksvI, UnnAjV, VXb, wBrIAf, JsYcyy, JhCI, fokw, UXmH, qgIskn, tSlTY, bAf, dHOELr, DGXhXA, EqEvHa, rwAy, jDH, jPeOWH, uUb, FBaCK, rXRmup, Ndm, RAw, DVhRD, EDDjXV, nDn, MepdBi, DhPFS, rCUYP, fzouE, xryzP, KaORwk, ybw, YqQyT, yJSof, zwbC, bofWPi, ewuj, CUYS, zIceER, xWofUV, zpafuS, GAGNN, LYlMs, AwTika, OWsY, oHI, HdkgP, pAZtS, Apos, rrrs, TIwud, rPWVr, KSg, SsNSP, QMpn, uEsfz, kBGwb, Ugxoe, qkfqOi, nKHw, Sett, tnLq, bvq, OEop, BEi, kak, UFB, OrG, iAepf,
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